Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging? (Q42590449)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212467%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging? (English)

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19 January 2020

3

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19 January 2020

author name string

Alejandro P Ugalde

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212467%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Guillermo Mariño

series ordinal

2

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19 January 2020

publication date

1 December 2010

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19 January 2020

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19 January 2020

volume

2

1 reference

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19 January 2020

issue

12

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19 January 2020

page(s)

1017-1022

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Autophagy and aging: lessons from progeria models

19 January 2020

cites work

1 reference

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Growth hormone, insulin and aging: the benefits of endocrine defects

28 May 2018

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Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.

28 May 2018

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Progeria syndromes and ageing: what is the connection?

28 May 2018

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With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

28 May 2018

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Linking functional decline of telomeres, mitochondria and stem cells during ageing

28 May 2018

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The central role of chromatin maintenance in aging

28 May 2018

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Human insulin/IGF-1 and familial longevity at middle age.

28 May 2018

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Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions

28 May 2018

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Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.

28 May 2018

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DNA Damage, Aging, and Cancer

28 May 2018

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Recent progress in the biology and physiology of sirtuins

28 May 2018

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Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

28 May 2018

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Accelerated ageing: from mechanism to therapy through animal models

28 May 2018

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Puzzles, promises and a cure for ageing

28 May 2018

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

28 May 2018

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28 May 2018

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Premature aging in mice activates a systemic metabolic response involving autophagy induction.

28 May 2018

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Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

28 May 2018

1 reference

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Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

28 May 2018

1 reference

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Endocrine regulation of ageing

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034170

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome

28 May 2018

1 reference

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A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

28 May 2018

1 reference

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Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions

28 May 2018

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28 May 2018

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Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034170

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

28 May 2018

1 reference

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Genetic mouse models of extended lifespan

28 May 2018

1 reference

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Genetic pathways that regulate ageing in model organisms

28 May 2018

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Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy

28 May 2018

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A C. elegans mutant that lives twice as long as wild type

28 May 2018

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Aging: past, present and future

28 May 2018

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Hutchinson-Gilford progeria syndrome: review of the phenotype.

16 August 2018

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Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

16 August 2018

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Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

16 August 2018

1 reference

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Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Response to nutritional and growth hormone treatment in progeria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212467%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

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19 January 2020

1 reference