Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb. (Q46022696)

18 December 2017

title

Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb. (English)

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18 December 2017

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K Kitagawa

1

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18 December 2017

Y Hiramatsu

2

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18 December 2017

C Uchida

3

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18 December 2017

T Isobe

4

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18 December 2017

T Hattori

5

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18 December 2017

T Oda

6

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18 December 2017

K Shibata

7

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18 December 2017

S Nakamura

8

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18 December 2017

A Kikuchi

9

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18 December 2017

M Kitagawa

10

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18 December 2017

language of work or name

English

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publication date

4 May 2009

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18 December 2017

published in

Oncogene

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18 December 2017

volume

28

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18 December 2017

page(s)

2393-2405

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18 December 2017

issue

25

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.111

exact match

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Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

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ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

21 January 2018

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21 January 2018

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p53 suppresses the c-Myb-induced activation of heat shock transcription factor 3.

21 January 2018

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A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta

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Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

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The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

21 January 2018

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Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

21 January 2018

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21 January 2018

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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

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SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock

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31 March 2020

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Identification of protein instability determinants in the carboxy-terminal region of c-Myb removed as a result of retroviral integration in murine monocytic leukemias

31 March 2020

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Identifiers

DOI

10.1038/ONC.2009.111

1 reference

18 December 2017

Dimensions Publication ID

0 references

1 reference

18 December 2017