Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. (Q46772713)

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8 January 2020

title

Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells (English)

1 reference

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oral squamous cell carcinoma

8 January 2020

main subject

phosphorylation

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1 reference

Solachuddin Jauhari Arief Ichwan

inferred from title

author

1

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8 January 2020

author name string

Yamada S

2

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8 January 2020

Sumrejkanchanakij P

3

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8 January 2020

Ibrahim-Auerkari E

4

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8 January 2020

Eto K

5

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8 January 2020

Ikeda MA

6

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8 January 2020

language of work or name

English

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publication date

1 February 2006

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8 January 2020

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8 January 2020

volume

25

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8 January 2020

issue

8

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8 January 2020

page(s)

1216-1224

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209158

8 January 2020

exact match

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cites work

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Regulation of p53 function and stability by phosphorylation

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Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.

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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

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Post-translational modification of p53 in tumorigenesis

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

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Cell biology. PARP-1--a perpetrator of apoptotic cell death?

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

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Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function

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HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

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Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

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Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

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p53: puzzle and paradigm

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A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

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Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

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To die or not to die: how does p53 decide?

21 January 2018

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Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator

21 January 2018

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Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

21 January 2018

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Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

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21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1209158

1 reference

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