Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts. (Q51919937)

17 April 2018

title

Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts. (English)

1 reference

17 April 2018

author name string

K Masuda

1

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17 April 2018

Y Ishikawa

2

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17 April 2018

I Onoyama

3

1 reference

17 April 2018

M Unno

4

1 reference

17 April 2018

I M de Alborán

5

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17 April 2018

K I Nakayama

6

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17 April 2018

K Nakayama

7

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17 April 2018

language of work or name

English

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publication date

21 December 2009

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17 April 2018

published in

Oncogene

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17 April 2018

volume

29

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17 April 2018

issue

12

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17 April 2018

page(s)

1798-1809

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17 April 2018

https://scigraph.springernature.com/pub.10.1038/onc.2009.469

exact match

0 references

cites work

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Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma

21 January 2018

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Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

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Nucleophosmin is required for DNA integrity and p19Arf protein stability

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Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

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c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death

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Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes

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p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors

21 January 2018

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Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a).

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sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

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Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7.

21 January 2018

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The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression

21 January 2018

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Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

21 January 2018

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Functional conservation of mouse Notch receptor family members

21 January 2018

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

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DNA copy number losses in human neoplasms

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

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Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation

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The genetics of malignant melanoma

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Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

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Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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Plat-E: an efficient and stable system for transient packaging of retroviruses

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Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1

21 January 2018

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

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Ubiquitin ligases: cell-cycle control and cancer

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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

21 January 2018

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Fbxw7 in cell cycle exit and stem cell maintenance: insight from gene-targeted mice

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Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

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p19ARF directly and differentially controls the functions of c-Myc independently of p53.

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Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

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Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation

21 January 2018

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Conspirators in a capital crime: co-deletion of p18INK4c and p16INK4a/p14ARF/p15INK4b in glioblastoma multiforme

21 January 2018

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

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Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.469

Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

21 January 2018

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Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

21 January 2018

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FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

21 January 2018

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.469

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.469

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.469

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.469

p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor beta1

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.469

Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.469

Notch targets the Cdk inhibitor Xic1 to regulate differentiation but not the cell cycle in neurons

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.469

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.469

1 reference

17 April 2018

PubMed ID

20023701

1 reference

17 April 2018