Electrophilic properties of itaconate and derivatives regulate the&#160;IκBζ-ATF3 inflammatory axis. (Q52579425)

14 July 2018

title

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis. (English)

1 reference

14 July 2018

Eynav Klechevsky

28

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Miguel P. Soares

Miguel P Soares

19

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Dustin Duncan

11

Dustin Duncan

1 reference

14 July 2018

Thomas P Roddy

25

Thomas P Roddy

1 reference

14 July 2018

Maxim N Artyomov

31

Maxim N Artyomov

1 reference

14 July 2018

Gwendalyn J. Randolph

30

Gwendalyn J Randolph

1 reference

14 July 2018

author name string

Monika Bambouskova

1

1 reference

14 July 2018

Laurent Gorvel

2

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14 July 2018

Vicky Lampropoulou

3

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14 July 2018

Alexey Sergushichev

4

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14 July 2018

Ekaterina Loginicheva

5

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14 July 2018

Kendall Johnson

6

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14 July 2018

Daniel Korenfeld

7

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14 July 2018

Mary Elizabeth Mathyer

8

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14 July 2018

Hyeryun Kim

9

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14 July 2018

Li-Hao Huang

10

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14 July 2018

Howard Bregman

12

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14 July 2018

Abdurrahman Keskin

13

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14 July 2018

Andrea Santeford

14

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Rajendra S Apte

15

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14 July 2018

Raghav Sehgal

16

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14 July 2018

Britney Johnson

17

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Gaya K Amarasinghe

18

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14 July 2018

Takashi Satoh

20

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Shizuo Akira

21

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14 July 2018

Tsonwin Hai

22

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14 July 2018

Cristina de Guzman Strong

23

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14 July 2018

Karine Auclair

24

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14 July 2018

Scott A Biller

26

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14 July 2018

Marko Jovanovic

27

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14 July 2018

Kelly M Stewart

29

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14 July 2018

language of work or name

English

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publication date

18 April 2018

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14 July 2018

published in

Nature

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14 July 2018

volume

556

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14 July 2018

page(s)

501-504

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14 July 2018

issue

7702

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14 July 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6037913/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/6037913

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41586-018-0052-z

0 references

cites work

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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

15 July 2018

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15 July 2018

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Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels

15 July 2018

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IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.

15 July 2018

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15 July 2018

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IκBζ is a key driver in the development of psoriasis

15 July 2018

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15 July 2018

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15 July 2018

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Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization

15 July 2018

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Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.

15 July 2018

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism

15 July 2018

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limma powers differential expression analyses for RNA-sequencing and microarray studies

15 July 2018

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Modulation of oxidative stress as an anticancer strategy

15 July 2018

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The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

15 July 2018

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15 July 2018

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IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA.

15 July 2018

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Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer

15 July 2018

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

15 July 2018

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A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis

15 July 2018

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Transcriptional control of the inflammatory response

15 July 2018

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15 July 2018

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Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

15 July 2018

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Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

15 July 2018

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Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

15 July 2018

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Role for activating transcription factor 3 in stress-induced beta-cell apoptosis

15 July 2018

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15 July 2018

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15 July 2018

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

15 July 2018

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Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis.

15 July 2018

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13 August 2018

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Model-based metabolic engineering enables high yield itaconic acid production by Escherichia coli.

13 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037913

IκBζ is a transcriptional key regulator of CCL2/MCP-1.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037913

Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.

13 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037913

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13 August 2018

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13 August 2018

1 reference

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13 August 2018

1 reference

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Fast gene set enrichment analysis

13 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41586-018-0052-Z

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41586-018-0052-Z

1 reference

14 July 2018

PMCID

6037913

1 reference

14 July 2018

PubMed ID

29670287

1 reference

14 July 2018