Cancer metabolism: key players in metabolic reprogramming (Q26827663)

language of work or name

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March 2013

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104

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issue

3

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page(s)

275-81

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Regulation of cancer cell metabolism

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The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

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p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

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Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

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The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

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Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

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Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

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Cancer: Sacrifice for survival.

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Analysis of the IDH1 codon 132 mutation in brain tumors

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IDH1 and IDH2 mutations in gliomas

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

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IDH mutations in glioma and acute myeloid leukemia

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

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Lipid metabolism in cancer

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

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Mitochondrial fumarate reductase as a target of chemotherapy: from parasites to cancer cells

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The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments

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Electron-transfer complexes in Ascaris mitochondria

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Non-[18F]FDG PET in clinical oncology

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Targeting cancer metabolism: a therapeutic window opens

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Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

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12 December 2020

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

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12 December 2020

O(2) extraction is a key parameter determining the oxygenation status of malignant tumors and normal tissues.

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12 December 2020

Tumor Mitochondria and the Bioenergetics of Cancer Cells

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12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

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12 December 2020

Kinetic evidence for the presence of two forms of M2-type pyruvate kinase in rat small intestine

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12 December 2020

Glycolytic enzymes can modulate cellular life span

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12 December 2020

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

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12 December 2020

HIF-1 and human disease: one highly involved factor

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12 December 2020

The functions of Myc proteins

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12 December 2020

Energy metabolism of tumor cells. Requirement for a form of hexokinase with a propensity for mitochondrial binding

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12 December 2020

Fructose 2,6-bisphosphate. A new activator of phosphofructokinase

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12 December 2020

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

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12 December 2020

On the Origin of Cancer Cells

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12 December 2020