The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation (Q28511737)

25 January 2017

title

The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation (English)

1 reference

WW domain containing E3 ubiquitin protein ligase 1

25 January 2017

1 reference

1 reference

GOA release 2020-03-11

author name string

Shu-Mang Feng

1

1 reference

25 January 2017

Rebecca S. Muraoka-Cook

2

1 reference

25 January 2017

Debra Hunter

3

1 reference

25 January 2017

Melissa A. Sandahl

4

1 reference

25 January 2017

Laura S. Caskey

5

1 reference

25 January 2017

Keiji Miyazawa

6

1 reference

25 January 2017

Azeddine Atfi

7

1 reference

25 January 2017

H. Shelton Earp

8

1 reference

25 January 2017

language of work or name

English

0 references

publication date

1 February 2009

1 reference

Molecular and Cellular Biology

25 January 2017

published in

1 reference

25 January 2017

volume

29

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25 January 2017

issue

3

1 reference

25 January 2017

page(s)

892–906

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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

25 January 2017

cites work

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WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

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Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

19 March 2017

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19 March 2017

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WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

19 March 2017

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ErbB2 degradation mediated by the co-chaperone protein CHIP

19 March 2017

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Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

19 March 2017

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An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

19 March 2017

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Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein

19 March 2017

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gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

19 March 2017

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Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4

19 March 2017

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A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis

19 March 2017

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Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

19 March 2017

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Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase

19 March 2017

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19 March 2017

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A novel juxtamembrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester

19 March 2017

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Characterization of a novel protein-binding module--the WW domain

19 March 2017

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ERBB receptors and cancer: the complexity of targeted inhibitors

19 March 2017

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

7 April 2017

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Association of Wwox with ErbB4 in breast cancer.

7 April 2017

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The Nedd4-like family of E3 ubiquitin ligases and cancer

29 September 2017

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HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4.

29 September 2017

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The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation

29 September 2017

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The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation

29 September 2017

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The amplified WWP1 gene is a potential molecular target in breast cancer

29 September 2017

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Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1.

29 September 2017

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Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.

29 September 2017

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Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases

29 September 2017

1 reference

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Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression.

29 September 2017

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The ErbB/HER receptor protein-tyrosine kinases and cancer

29 September 2017

1 reference

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Ubiquitin and breast cancer

29 September 2017

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The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

29 September 2017

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29 September 2017

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E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

29 September 2017

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Type 1 growth factor receptor expression in node positive breast cancer: adverse prognostic significance of c-erbB-4

29 September 2017

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ErbBs in mammary development

29 September 2017

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Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630679

Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities

29 September 2017

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Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

29 September 2017

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Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.

29 September 2017

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Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.

29 September 2017

1 reference

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Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation

29 September 2017

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Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breast

2 June 2018

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Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment

27 November 2018

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27 November 2018

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Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer

27 November 2018

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EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival.

27 November 2018

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Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630679

Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancers

27 November 2018

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12 December 2020

Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay

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12 December 2020

c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer

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12 December 2020

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

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12 December 2020

Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains

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12 December 2020