Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway (Q33211246)

24 July 2017

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway (English)

1 reference

24 July 2017

0 references

1 reference

Christian Scholz

1

1 reference

24 July 2017

Thomas Wieder

2

1 reference

24 July 2017

Lilian Stärck

3

1 reference

24 July 2017

Frank Essmann

4

1 reference

24 July 2017

Klaus Schulze-Osthoff

5

1 reference

24 July 2017

Bernd Dörken

6

1 reference

24 July 2017

Peter T Daniel

7

1 reference

24 July 2017

language of work or name

English

0 references

publication date

1 March 2005

1 reference

24 July 2017

1 reference

24 July 2017

24

1 reference

24 July 2017

11

1 reference

24 July 2017

1904-1913

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208233

24 July 2017

0 references

cites work

Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Cell death beyond apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Guardians of cell death: the Bcl-2 family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

The kiss of death: promises and failures of death receptors and ligands in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

More than one way to die: apoptosis, necrosis and reactive oxygen damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Mitochondrial control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

The CD95(APO-1/Fas) DISC and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Mitochondrial membrane potential monitored by JC-1 dye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Cell death: the significance of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Alkylating DNA damage stimulates a regulated form of necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

7 January 2021

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

7 January 2021

Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208233

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208233

1 reference

Dimensions Publication ID

24 July 2017

0 references

1 reference