Transgenic animals relevant to Alzheimer's disease (Q33588638)

28 July 2017

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title

Transgenic animals relevant to Alzheimer's disease (English)

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28 July 2017

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Seabrook GR

1

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28 July 2017

Rosahl TW

series ordinal

2

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28 July 2017

publication date

1 January 1999

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28 July 2017

number of pages

17

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based on heuristic

inferred from page(s)

published in

Neuropharmacology

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28 July 2017

volume

38

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28 July 2017

issue

1

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28 July 2017

page(s)

1-17

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Memory suppressor genes: inhibitory constraints on the storage of long-term memory

28 July 2017

cites work

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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

7 January 2021

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Involvement of LTP in memory: Are we “searching under the street light”?

7 January 2021

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Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

7 January 2021

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7 January 2021

Supersonic congenics?

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Alpha-2 macroglobulin is genetically associated with Alzheimer disease

7 January 2021

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A synaptic model of memory: long-term potentiation in the hippocampus

7 January 2021

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Postsynaptic induction and presynaptic expression of hippocampal long-term depression

7 January 2021

1 reference

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Reduced nitric oxide responsive soluble guanylyl cyclase activity in the superior temporal cortex of patients with Alzheimer's disease.

7 January 2021

1 reference

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

7 January 2021

1 reference

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

7 January 2021

1 reference

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Neuron loss in APP transgenic mice

7 January 2021

1 reference

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Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

7 January 2021

1 reference

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Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain

7 January 2021

1 reference

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Abnormal hippocampal spatial representations in alphaCaMKIIT286A and CREBalphaDelta- mice.

7 January 2021

1 reference

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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Regulation of EPSPs by the synaptic activation of GABAB autoreceptors in rat hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

GABAB autoreceptors regulate the induction of LTP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

7 January 2021

1 reference

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Prevalence and types of dementia in the very old: results from the Canadian Study of Health and Aging.

7 January 2021

1 reference

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Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Alzheimer's disease. A technical KO of amyloid-beta peptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Amyloid, the presenilins and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Diagnosis of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mutations in the transmembrane domain of APP altering gamma-secretase specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Control of memory formation through regulated expression of a CaMKII transgene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Alzheimer's disease: a re-examination of the amyloid hypothesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

A mouse model for Down syndrome exhibits learning and behaviour deficits.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Loss of recent memory after bilateral hippocampal lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Modulation of long-term potentiation in CA1 region of mouse hippocampal brain slices by GABAA receptor benzodiazepine site ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Alzheimer's disease: genotypes, phenotypes, and treatments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Skeletal and CNS defects in Presenilin-1-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Spatial learning and memory: the beginning of a dream

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Subregion- and cell type-restricted gene knockout in mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Effects of Alzheimer's disease-related beta amyloid protein fragments on enzymes metabolizing phosphoinositides in brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Mechanisms of neuronal degeneration in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

Signal transduction mechanisms in Alzheimer disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900170-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0028-3908(98)00170-1

1 reference

release_dyg27qggtrculjlrc5mqjylzxe

28 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/dyg27qggtrculjlrc5mqjylzxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference