Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets (Q34464568)

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English	Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets	scientific article

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scholarly article

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Europe PubMed Central

2 August 2017

Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets (English)

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Europe PubMed Central

2 August 2017

genome-wide association study

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based on heuristic

inferred from title

object named as

Elin Hall

5

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object named as

Karl Bacos

3

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object named as

Tina Rönn

8

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object named as

Charlotte Ling

9

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author name string

Anders H Olsson

1

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Europe PubMed Central

2 August 2017

Petr Volkov

2

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Europe PubMed Central

2 August 2017

Tasnim Dayeh

4

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Europe PubMed Central

2 August 2017

Emma A Nilsson

6

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Europe PubMed Central

2 August 2017

Claes Ladenvall

7

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Europe PubMed Central

2 August 2017

publication date

6 November 2014

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

10

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Europe PubMed Central

2 August 2017

11

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Europe PubMed Central

2 August 2017

e1004735

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Europe PubMed Central

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

6 November 2014

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April 2022 Public Data File from Crossref

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Immune therapy in type 1 diabetes mellitus

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DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

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A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci

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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

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Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes

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Genomics, type 2 diabetes, and obesity

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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

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PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

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Shared and distinct genetic variants in type 1 diabetes and celiac disease

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Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth

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Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

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Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes

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Glutathione and apoptosis

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lumi: a pipeline for processing Illumina microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Perceptions of epigenetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Adjusting batch effects in microarray expression data using empirical Bayes methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Epigenetic transgenerational actions of endocrine disruptors and male fertility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Beta-cell CaV channel regulation in physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

An update of the HLA genomic region, locus information and disease associations: 2004.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Epigenetic germline inheritance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Genetics of type 1 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

DNA methylation patterns and epigenetic memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Autoimmune type 1 diabetes: resolved and unresolved issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

DNA methylation in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

The detection of disease clustering and a generalized regression approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

In situ analysis of pancreatic islets in rats developing diabetes. Appearance of nonendocrine cells with surface MHC class II antigens and cytoplasmic insulin immunoreactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222689

6 July 2018

DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

High density DNA methylation array with single CpG site resolution

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects--impact of 5 days of high-fat overfeeding

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Pre- and postnatal methyl deficiency in the rat differentially alters glucose homeostasis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Differences in immunohistochemical expression of xenobiotic-metabolizing enzymes between normal pancreas, chronic pancreatitis and pancreatic cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Clinical evaluation of insulin resistance and beta-cell function by the homeostasis model assessment in patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

The polymorphism (-600 C>A) of CpG methylation site at the promoter region of CYP17A1 and its association of male infertility and testosterone levels.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004735

21 January 2018

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/25375650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Insulin sensitivity and beta cell function in female systemic lupus erythematosus patients]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25375650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogen inactivation of human serum facilitates its clinical use for islet cell culture and subsequent transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25375650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1004735

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

ResearchGate publication ID

0 references

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