ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice. (Q34479990)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice (English)

1 reference

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17 January 2020

2

1 reference

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17 January 2020

Wei Tong

5

1 reference

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17 January 2020

author name string

Safak Yalcin

1

1 reference

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17 January 2020

Sathish Kumar Mungamuri

3

1 reference

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17 January 2020

Xin Zhang

4

1 reference

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17 January 2020

Rani Sellers

6

1 reference

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17 January 2020

Saghi Ghaffari

7

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17 January 2020

language of work or name

English

0 references

publication date

26 November 2010

1 reference

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17 January 2020

1 reference

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17 January 2020

volume

29

1 reference

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17 January 2020

issue

24

1 reference

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17 January 2020

page(s)

4118-4131

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Lnk constrains myeloproliferative diseases in mice

17 January 2020

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Regulation of PTP1B via glutathionylation of the active site cysteine 215

6 July 2018

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Direct control of the Forkhead transcription factor AFX by protein kinase B

6 July 2018

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Hematopoietic growth factors signal through the formation of reactive oxygen species

6 July 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

6 July 2018

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The free radical theory of aging matures

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB.

6 July 2018

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AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation.

21 January 2018

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Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

21 January 2018

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Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

21 January 2018

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Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

21 January 2018

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

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Redox regulation of Cdc25C.

21 January 2018

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Proliferative kinetics and differentiation of murine blast cell colonies in culture: evidence for variable G0 periods and constant doubling rates of early pluripotent hemopoietic progenitors

21 January 2018

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Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

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Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.

21 January 2018

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Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.

21 January 2018

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Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms.

21 January 2018

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PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.292

Myeloproliferative disorders

21 January 2018

1 reference

12 December 2020

Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B

1 reference

12 December 2020

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

1 reference

12 December 2020

Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate in vitro

1 reference

12 December 2020

Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lymphomyeloid differentiation in long-term marrow "switch" cultures

1 reference

12 December 2020

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2010.292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21113129

1 reference