Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation (Q35585661)

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scientific article published on 3 January 2007

Language	Label	Description	Also known as
English	Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation	scientific article published on 3 January 2007

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

9 references

14 March 2019

24 March 2019

30 June 2019

25 June 2019

5 August 2019

7 October 2019

10 October 2019

18 November 2019

19 July 2022

Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation (English)

1 reference

Europe PubMed Central

9 August 2017

type-1 diabetes

8 references

14 March 2019

24 March 2019

30 June 2019

25 June 2019

5 August 2019

7 October 2019

10 October 2019

18 November 2019

1 reference

5 August 2019

human digestive system

1 reference

7 October 2019

endocrine system

1 reference

10 October 2019

1 reference

18 November 2019

author name string

Jiaqiang Ren

1

1 reference

Europe PubMed Central

9 August 2017

Ping Jin

2

1 reference

Europe PubMed Central

9 August 2017

Ena Wang

3

1 reference

Europe PubMed Central

9 August 2017

Eric Liu

4

1 reference

Europe PubMed Central

9 August 2017

David M Harlan

5

1 reference

Europe PubMed Central

9 August 2017

Xin Li

6

1 reference

Europe PubMed Central

9 August 2017

David F Stroncek

7

1 reference

Europe PubMed Central

9 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

3 January 2007

10 references

Europe PubMed Central

9 August 2017

14 March 2019

24 March 2019

30 June 2019

25 June 2019

5 August 2019

7 October 2019

10 October 2019

18 November 2019

19 July 2022

Journal of Translational Medicine

10 references

Europe PubMed Central

9 August 2017

14 March 2019

24 March 2019

30 June 2019

25 June 2019

5 August 2019

7 October 2019

10 October 2019

18 November 2019

19 July 2022

5

1 reference

Europe PubMed Central

9 August 2017

1

1 reference

Europe PubMed Central

9 August 2017

copyright license

Creative Commons Attribution 2.0 Generic

9 references

Europe PubMed Central

14 March 2019

Europe PubMed Central

24 March 2019

Europe PubMed Central

30 June 2019

Europe PubMed Central

25 June 2019

Europe PubMed Central

5 August 2019

Europe PubMed Central

7 October 2019

Europe PubMed Central

10 October 2019

Europe PubMed Central

18 November 2019

Europe PubMed Central

19 July 2022

copyright status

0 references

on focus list of Wikimedia project

0 references

https://scigraph.springernature.com/pub.10.1186/1479-5876-5-1

0 references

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

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Regulation of the insulin gene by glucose and fatty acids

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In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion

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The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

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Coping with stress: eIF2 kinases and translational control

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Cdk5-dependent regulation of glucose-stimulated insulin secretion.

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Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004.

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27 July 2018

Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans

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27 July 2018

MafA is a key regulator of glucose-stimulated insulin secretion

1 reference

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27 July 2018

ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter

1 reference

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27 July 2018

Insulin independence after living-donor distal pancreatectomy and islet allotransplantation

1 reference

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27 July 2018

The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription

1 reference

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27 July 2018

Pancreatic islet transplantation

1 reference

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27 July 2018

Regeneration of the pancreatic beta cell

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27 July 2018

Mortality assessment for pancreas transplants

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27 July 2018

Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny

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27 July 2018

Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.

1 reference

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27 July 2018

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

1 reference

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27 July 2018

Stem-cell therapy for diabetes mellitus.

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27 July 2018

In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow

1 reference

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27 July 2018

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

1 reference

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27 July 2018

Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience

1 reference

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27 July 2018

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets

1 reference

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27 July 2018

Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells

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27 July 2018

Insulin staining of ES cell progeny from insulin uptake.

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27 July 2018

Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells

1 reference

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27 July 2018

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins

1 reference

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27 July 2018

PDX-1 mediates glucose responsiveness of GAD(67), but not GAD(65), gene transcription in islets of Langerhans

1 reference

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27 July 2018

A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets

1 reference

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27 July 2018

Short-term regulation of insulin gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Regulation of insulin gene transcription

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion

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27 July 2018

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells

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27 July 2018

Molecular determinants of exocytosis

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27 July 2018

Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation

1 reference

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27 July 2018

Mitochondrial function in normal and diabetic beta-cells

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27 July 2018

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

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27 July 2018

Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.

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27 July 2018

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

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27 July 2018

Insulin production by human embryonic stem cells

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27 July 2018

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

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27 July 2018

The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells

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27 July 2018

Beta-granule transport and exocytosis

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27 July 2018

Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell

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27 July 2018

Regulation of insulin gene transcription

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27 July 2018

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

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27 July 2018

Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2.

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27 July 2018

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

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27 July 2018

Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter

1 reference

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27 July 2018

The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

1 reference

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27 July 2018

Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

1 reference

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27 July 2018

Glucose induces early growth response gene (Egr-1) expression in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation

1 reference

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27 July 2018

Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

27 July 2018

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

1 reference

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27 July 2018

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E

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27 July 2018

Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

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27 July 2018

The pyruvate kinase gene as a model for studies of glucose-dependent regulation of gene expression in the endocrine pancreatic beta-cell type.

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27 July 2018

Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells

1 reference

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27 July 2018

Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).

1 reference

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27 July 2018

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

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27 July 2018

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

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27 July 2018

Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell

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27 July 2018

Automated method for isolation of human pancreatic islets

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27 July 2018

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

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27 July 2018

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

1 reference

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27 July 2018

Insulin independence after islet transplantation into type I diabetic patient

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27 July 2018

Glucose induces insulin gene transcription in a murine pancreatic beta-cell line

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27 July 2018

Human islet transplantation: a preliminary report

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27 July 2018

Diabetes cure--is the glass half full?

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26 September 2018

International trial of the Edmonton protocol for islet transplantation.

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26 September 2018

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

1 reference

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26 September 2018

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

1 reference

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26 September 2018

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

1 reference

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26 September 2018

Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes

1 reference

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26 September 2018

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1.

1 reference

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26 September 2018

The beneficial effects of pancreas transplant alone on diabetic nephropathy

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26 September 2018

The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Hepatic regeneration and enforced PDX-1 expression accelerate transdifferentiation in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Survival after pancreas transplantation in patients with diabetes and preserved kidney function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Insulin granule dynamics in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Insulin does not mediate glucose stimulation of proinsulin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Endoplasmic reticulum stress and the development of diabetes: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Short-term regulation of insulin gene transcription by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769476

26 September 2018

A long-term functioning human pancreatic islet allotransplant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplantation of intact pancreatic islets in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational control of proinsulin synthesis by glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of GLUT1 and GLUT2 glucose transporter isoforms in rat islets of Langerhans and their regulation by glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the human insulin promoter in primary cultured islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the insulin gene by glucose: stimulation of trans-activation potency of human PDX-1 N-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro transdifferentiation of mature hepatocytes into insulin-producing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17201925

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1479-5876-5-1

1 reference

Europe PubMed Central

9 August 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

ResearchGate publication ID

0 references

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