Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection. (Q36278041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22987800%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection (English)

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13 February 2020

1

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13 February 2020

author name string

Lucie Carrié

2

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13 February 2020

Doron Merkler

3

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13 February 2020

Michael J Bevan

4

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13 February 2020

Dietmar Zehn

5

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13 February 2020

language of work or name

English

0 references

publication date

17 September 2012

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Journal of Experimental Medicine

13 February 2020

published in

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13 February 2020

volume

209

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13 February 2020

issue

10

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13 February 2020

page(s)

1769-1779

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Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

13 February 2020

cites work

1 reference

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Regulatory T cells: mechanisms of differentiation and function

30 September 2017

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Selection of self-reactive T cells in the thymus

30 September 2017

1 reference

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Control of central and peripheral tolerance by Aire

30 September 2017

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Lack of original antigenic sin in recall CD8(+) T cell responses

30 September 2017

1 reference

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Antigen presentation in the thymus for positive selection and central tolerance induction

30 September 2017

1 reference

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30 September 2017

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Type 1 diabetes as a relapsing-remitting disease?

30 September 2017

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Mobilizing the low-avidity T cell repertoire to kill tumors

30 September 2017

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miR-181a is an intrinsic modulator of T cell sensitivity and selection

30 September 2017

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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

30 September 2017

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T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

30 September 2017

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Molecular mimicry, microbial infection, and autoimmune disease: evolution of the concept.

30 September 2017

1 reference

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The timing of TCR alpha expression critically influences T cell development and selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

30 September 2017

1 reference

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Negative selection--clearing out the bad apples from the T-cell repertoire

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Positive and negative selection of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Projection of an immunological self shadow within the thymus by the aire protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Memory CD8(+) T cells undergo peripheral tolerance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Negative selection of thymocytes expressing the D10 TCR

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Ontogeny of T cell tolerance to peripherally expressed antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

T-cell-receptor affinity and thymocyte positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Complete but curtailed T-cell response to very low-affinity antigen

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

29 June 2018

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Contributions of the lymphocytic choriomeningitis virus glycoprotein and polymerase to strain-specific differences in murine liver pathogenicity

29 June 2018

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HOPE fixation: a novel fixing method and paraffin-embedding technique for human soft tissues.

22 September 2018

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Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection

22 September 2018

1 reference

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V beta 5+ T cell receptors skew toward OVA+H-2Kb recognition

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457731

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

22 September 2018

1 reference

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Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20120905

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20120905

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20120905

Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice

21 January 2018

1 reference

12 December 2020

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

1 reference

12 December 2020

Characterization of CD8+ T Lymphocytes That Persist After Peripheral Tolerance to a Self Antigen Expressed in the Pancreas

1 reference

12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20120905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22987800%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22987800%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22987800%20AND%20SRC:MED&resulttype=core&format=json