Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage (Q36347245)

13 August 2017

Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage (English)

1 reference

13 August 2017

0 references

Y Tong

1

1 reference

13 August 2017

H Ying

2

1 reference

13 August 2017

R Liu

3

1 reference

13 August 2017

L Li

4

1 reference

13 August 2017

J Bergholz

5

1 reference

13 August 2017

Z-X Xiao

6

1 reference

13 August 2017

12 February 2015

1 reference

13 August 2017

Cell Death and Disease

1 reference

13 August 2017

6

1 reference

13 August 2017

e1640

1 reference

Creative Commons Attribution 4.0 International

13 August 2017

start time

1 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.

30 September 2017

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A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

30 September 2017

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Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins

30 September 2017

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Cellular mechanisms of tumour suppression by the retinoblastoma gene.

30 September 2017

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The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

30 September 2017

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One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma.

30 September 2017

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Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.

30 September 2017

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The retinoblastoma protein in osteoblast differentiation and osteosarcoma

30 September 2017

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Retinoblastoma regulatory pathway in lung cancer

30 September 2017

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RB and cell cycle progression

30 September 2017

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The role of cell cycle regulatory proteins in the pathogenesis of melanoma.

30 September 2017

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The retinoblastoma protein regulates pericentric heterochromatin

30 September 2017

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MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.

30 September 2017

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E2F-Rb complexes regulating transcription of genes important for differentiation and development

30 September 2017

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Phosphorylation-specific prolyl isomerization: is there an underlying theme?

30 September 2017

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Regulation of Raf-1 by direct feedback phosphorylation.

30 September 2017

1 reference

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The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth

30 September 2017

1 reference

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A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130

30 September 2017

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Prevalent overexpression of prolyl isomerase Pin1 in human cancers

30 September 2017

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

30 September 2017

1 reference

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Cellular targets of the SV40 small-t antigen in human cell transformation

30 September 2017

1 reference

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RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult

30 September 2017

1 reference

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Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

30 September 2017

1 reference

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Cyclin-dependent kinases and S phase control in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

A revised picture of the E2F transcriptional network and RB function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

30 September 2017

1 reference

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Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

30 September 2017

1 reference

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The Rb/E2F pathway: expanding roles and emerging paradigms

30 September 2017

1 reference

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RB-dependent S-phase response to DNA damage

30 September 2017

1 reference

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Structural basis for phosphoserine-proline recognition by group IV WW domains

30 September 2017

1 reference

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The retinoblastoma gene family in differentiation and development.

30 September 2017

1 reference

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The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

30 September 2017

1 reference

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Functions of the retinoblastoma protein

30 September 2017

1 reference

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The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Specific enzymatic dephosphorylation of the retinoblastoma protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Interaction between the retinoblastoma protein and the oncoprotein MDM2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Okadaic acid: a new probe for the study of cellular regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Control of pRB phosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Identification of a growth suppression domain within the retinoblastoma gene product

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Characterization of an E2F1-specific binding domain in pRB and its implications for apoptotic regulation.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669794

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25675300

12 December 2020

inferred from PubMed ID database lookup

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25675300

12 December 2020

inferred from PubMed ID database lookup

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25675300

12 December 2020

inferred from PubMed ID database lookup

Experimental models of human cancer

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2015.3

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CDDIS.2015.3

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

25675300

1 reference