BCL2 family in DNA damage and cell cycle control (Q36501194)

14 August 2017

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title

BCL2 family in DNA damage and cell cycle control (English)

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14 August 2017

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1

Zinkel S

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14 August 2017

Gross A

2

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PubMed ID

16763616

14 August 2017

Yang E

series ordinal

3

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14 August 2017

9 June 2006

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Cell Death & Differentiation

14 August 2017

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14 August 2017

13

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14 August 2017

1351-1359

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14 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401987

14 August 2017

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cites work

Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Activation of cyclin A-dependent protein kinases during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Diminished cell proliferation associated with the death-protective activity of Bcl-2

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bax alpha perturbs T cell development and affects cell cycle entry of T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 inhibition of T-cell proliferation is related to prolonged T-cell survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: independent prognostic role of p53 and bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Overexpression of Bcl-W in the testis disrupts spermatogenesis: revelation of a role of BCL-W in male germ cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BAX and BAK mediate p53-independent suppression of tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bad-deficient mice develop diffuse large B cell lymphoma

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BID: a novel BH3 domain-only death agonist

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Deletion of Bid impedes cell proliferation and hepatic carcinogenesis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Cell death: critical control points

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Translocation of full-length Bid to mitochondria during anoikis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

A role for proapoptotic BID in the DNA-damage response

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Proapoptotic BID is an ATM effector in the DNA-damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

ASPP proteins specifically stimulate the apoptotic function of p53

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Integral role of Noxa in p53-mediated apoptotic response

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

A model for p53-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

BID regulation by p53 contributes to chemosensitivity

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401987

1 reference

PubMed ID

16763616

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16763616