Pax5--a critical inhibitor of plasma cell fate (Q36570655)

15 August 2017

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title

Pax5--a critical inhibitor of plasma cell fate (English)

1 reference

15 August 2017

K-P Nera

1

1 reference

PubMed ID

16918686

15 August 2017

O Lassila

series ordinal

2

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15 August 2017

1 September 2006

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Scandinavian Journal of Immunology

15 August 2017

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15 August 2017

64

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15 August 2017

3

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15 August 2017

190-199

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Transcriptional regulatory cascades controlling plasma cell differentiation

15 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Regulatory mechanisms that determine the development and function of plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Regulation of plasma-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

An interfering form of Blimp-1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Reversion of B cell commitment upon loss of Pax5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Loss of Pax5 promotes plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Transcriptional control of early B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Transcriptional networks in developing and mature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Multiple hematopoietic cell lineages develop in vivo from transplanted Pax5-deficient pre-B I-cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5 determines B- versus T-cell fate and does not block early myeloid-lineage development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax-5 is essential for kappa sterile transcription during Ig kappa chain gene rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Pax5 activates immunoglobulin heavy chain V to DJ rearrangement in transgenic thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Dependence of BSAP repressor and activator functions on BSAP concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

B cell-specific activator protein prevents two activator factors from binding to the immunoglobulin J chain promoter until the antigen-driven stages of B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Transcriptional and translational control in the Mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Intraclonal generation of antibody mutants in germinal centres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Maturation of the immune response in germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Disruption of the Bcl6 gene results in an impaired germinal center formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Identification of negative regulatory regions within the first exon and intron of the BCL6 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Insight into lymphoid development by gene expression profiling of avian B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

AID is essential for immunoglobulin V gene conversion in a cultured B cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Increased ratio of targeted to random integration after transfection of chicken B cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Analysis of gene expression during myc oncogene-induced lymphomagenesis in the bursa of Fabricius

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Differential effect of B lymphocyte-induced maturation protein (Blimp-1) expression on cell fate during B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The AID enzyme induces class switch recombination in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The balance between Pax5 and Id2 activities is the key to AID gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Aiolos regulates B cell activation and maturation to effector state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Ikaros has a crucial role in regulation of B cell receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

The B cell-specific transcription factor BSAP regulates B cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

Mechanism of antigen-driven selection in germinal centres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.01809.X

10.1111/J.1365-3083.2006.01809.X

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16918686