The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation. (Q37135509)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18535165%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation (English)

1 reference

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8 January 2020

3

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8 January 2020

author name string

Taira Wada

series ordinal

1

1 reference

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8 January 2020

Hong Soon Kang

series ordinal

2

1 reference

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8 January 2020

Wen Xie

series ordinal

4

1 reference

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8 January 2020

publication date

5 June 2008

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Experimental Biology and Medicine

8 January 2020

published in

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8 January 2020

volume

233

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8 January 2020

issue

10

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8 January 2020

page(s)

1191-1201

1 reference

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8 January 2020

1 reference

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

14 September 2017

1 reference

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Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

14 September 2017

1 reference

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Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

14 September 2017

1 reference

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14 September 2017

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

14 September 2017

1 reference

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Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation.

14 September 2017

1 reference

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Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta

14 September 2017

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A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

14 September 2017

1 reference

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The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

14 September 2017

1 reference

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Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury

14 September 2017

1 reference

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LXR-dependent gene expression is important for macrophage survival and the innate immune response

14 September 2017

1 reference

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A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

14 September 2017

1 reference

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Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

14 September 2017

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Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism

14 September 2017

1 reference

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Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

14 September 2017

1 reference

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RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways

14 September 2017

1 reference

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All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

14 September 2017

1 reference

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Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

14 September 2017

1 reference

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Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

14 September 2017

1 reference

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Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis

14 September 2017

1 reference

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A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.

14 September 2017

1 reference

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

14 September 2017

1 reference

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X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

14 September 2017

1 reference

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The liver X receptor gene team: potential new players in atherosclerosis

14 September 2017

1 reference

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Identification of Reverb(alpha) as a novel ROR(alpha) target gene

14 September 2017

1 reference

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Vitamin D receptor as an intestinal bile acid sensor

14 September 2017

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Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

14 September 2017

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14 September 2017

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Biochemistry and reproductive endocrinology of estrogen sulfotransferase.

14 September 2017

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Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha

14 September 2017

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Nuclear receptors and lipid physiology: opening the X-files

14 September 2017

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The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes

14 September 2017

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Nuclear receptor minireview series

14 September 2017

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The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

14 September 2017

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

14 September 2017

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

14 September 2017

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

14 September 2017

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Role of LXRs in control of lipogenesis

14 September 2017

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

14 September 2017

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Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

14 September 2017

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14 September 2017

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In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism

14 September 2017

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Requirement for RORgamma in thymocyte survival and lymphoid organ development

14 September 2017

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14 September 2017

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14 September 2017

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Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD

14 September 2017

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14 September 2017

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

14 September 2017

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A novel isoform of the orphan nuclear receptor RORbeta is specifically expressed in pineal gland and retina

14 September 2017

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Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice

14 September 2017

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14 September 2017

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staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

14 September 2017

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An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

14 September 2017

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Transcriptional activation and repression by RORalpha, an orphan nuclear receptor required for cerebellar development

14 September 2017

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Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element

14 September 2017

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Thiazolidine diones, specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent antiarthritic activity.

14 September 2017

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Disruption of the nuclear hormone receptor RORalpha in staggerer mice

14 September 2017

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14 September 2017

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RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

14 September 2017

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Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

14 September 2017

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Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand

14 September 2017

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

14 September 2017

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Human cytochromes P450: problems and prospects

14 September 2017

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Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes

14 September 2017

1 reference

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Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

14 September 2017

1 reference

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

29 September 2017

1 reference

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Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha

29 September 2017

1 reference

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Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis

29 September 2017

1 reference

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Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor

27 June 2018

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Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma

27 June 2018

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Humanized xenobiotic response in mice expressing nuclear receptor SXR.

27 June 2018

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ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

27 June 2018

1 reference

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Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.

27 June 2018

1 reference

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Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

3 September 2018

1 reference

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LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver

3 September 2018

1 reference

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Enhanced susceptibility of staggerer (RORalphasg/sg) mice to lipopolysaccharide-induced lung inflammation.

3 September 2018

1 reference

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Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658633

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658633

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

3 September 2018

1 reference

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Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential

3 September 2018

1 reference

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Smooth muscle dysfunction in resistance arteries of the staggerer mouse, a mutant of the nuclear receptor RORalpha

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658633

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3181%2F0802-MR-50

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

21 January 2018

1 reference

12 December 2020

Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and species-difference between rat and human

1 reference

12 December 2020

A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

1 reference

12 December 2020

Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers

1 reference

12 December 2020

Expression and regulation of the nuclear receptor RORalpha in human vascular cells

1 reference

12 December 2020

Identifiers

DOI

10.3181/0802-MR-50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18535165%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18535165%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference