Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology (Q37286190)

scientific article published on January 2009

Language	Label	Description	Also known as
English	Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology	scientific article published on January 2009

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

title

Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology (English)

1 reference

stated in

Europe PubMed Central

19 August 2017

2

Aaron Ciechanover

1 reference

stated in

Europe PubMed Central

19 August 2017

Alan L Schwartz

1

1 reference

stated in

Europe PubMed Central

19 August 2017

1 January 2009

1 reference

stated in

Europe PubMed Central

19 August 2017

Annual Review of Pharmacology and Toxicology

1 reference

stated in

Europe PubMed Central

19 August 2017

49

1 reference

stated in

Europe PubMed Central

19 August 2017

73-96

1 reference

stated in

Europe PubMed Central

19 August 2017

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Regulated portals of entry into the cell

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Clinical factors predictive of outcome with bortezomib in patients with relapsed, refractory multiple myeloma

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Autophagosome formation: core machinery and adaptations

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Trinucleotide Repeat Disorders

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Emerging roles for ubiquitin and protein degradation in neuronal function

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

The p53-mdm-2 autoregulatory feedback loop

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Evaluation of HIF-1 inhibitors as anticancer agents

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Whole-body protein turnover in the healthy elderly.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Ubiquitin signals in the NF-kappaB pathway.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

The von Hippel-Lindau tumor suppressor protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Ubiquitin-mediated proteolysis: biological regulation via destruction

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

The aggravating role of the ubiquitin-proteasome system in neurodegenerative disease.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma:: final time-to-event results from the SUMMIT trial

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Kidney, splanchnic, and leg protein turnover in humans. Insight from leucine and phenylalanine kinetics.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.PHARMTOX.051208.165340

Identifiers

DOI

10.1146/ANNUREV.PHARMTOX.051208.165340

1 reference

stated in

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

PubMed ID

18834306

retrieved

19 August 2017

Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology (Q37286190)

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Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology (Q37286190)

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