Mitochondria and diabetes mellitus: untangling a conflictive relationship? (Q37612965)

21 August 2017

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title

Mitochondria and diabetes mellitus: untangling a conflictive relationship? (English)

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21 August 2017

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M Schiff

1

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21 August 2017

S Loublier

2

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21 August 2017

A Coulibaly

3

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21 August 2017

P Bénit

4

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21 August 2017

H Ogier de Baulny

5

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21 August 2017

P Rustin

6

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21 August 2017

publication date

11 October 2009

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Journal of Inherited Metabolic Disease

21 August 2017

published in

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21 August 2017

volume

32

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21 August 2017

issue

6

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21 August 2017

page(s)

684-698

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Muscular mitochondrial dysfunction and type 2 diabetes mellitus

21 August 2017

cites work

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Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

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Maternally inherited duplication of the mitochondrial genome in a syndrome of proximal tubulopathy, diabetes mellitus, and cerebellar ataxia

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[Mitochondrial control of apoptosis]

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Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia

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Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle

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Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

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Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function

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12 December 2020

Calorie restriction increases muscle mitochondrial biogenesis in healthy humans

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12 December 2020

The insulin-sensitizing effect of rosiglitazone in type 2 diabetes mellitus patients does not require improved in vivo muscle mitochondrial function

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12 December 2020

Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.

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Mitochondrial diabetes and its lessons for common Type 2 diabetes.

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How obesity causes diabetes: not a tall tale

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Mitochondrial DNA and disease

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Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.

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12 December 2020

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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12 December 2020

Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness

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12 December 2020

Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance

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12 December 2020

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12 December 2020

Maternally transmitted partial direct tandem duplication of mitochondrial DNA associated with diabetes mellitus

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12 December 2020

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

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12 December 2020

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

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12 December 2020

Molecular mechanisms of mitochondrial diabetes (MIDD).

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12 December 2020

Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

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12 December 2020

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12 December 2020

A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians.

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12 December 2020

Lessons that can be learned from patients with diabetogenic mutations in mitochondrial DNA: implications for common type 2 diabetes.

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12 December 2020

Mitochondrial function in normal and diabetic beta-cells

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12 December 2020

Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

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12 December 2020

Mitochondrial damages and the regulation of insulin secretion

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12 December 2020

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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12 December 2020

Mitochondrial diabetes revisited

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12 December 2020

Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding

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12 December 2020

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

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12 December 2020

Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes

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12 December 2020

Mitochondria--a nexus for aging, calorie restriction, and sirtuins?

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12 December 2020

Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study

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12 December 2020

Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus

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12 December 2020

PPAR gamma and human metabolic disease

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12 December 2020

Etiology of insulin resistance

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12 December 2020

Premature ageing in mice expressing defective mitochondrial DNA polymerase

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12 December 2020

Insulin signalling and the regulation of glucose and lipid metabolism

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12 December 2020

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

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12 December 2020

Mitochondrial Respiration Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes

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12 December 2020

Is energy deficiency good in moderation?

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12 December 2020

Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation

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12 December 2020

Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia

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12 December 2020

Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

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12 December 2020

Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes

1 reference

12 December 2020

Congenital hypoplastic anemia, diabetes, and severe renal tubular dysfunction associated with a mitochondrial DNA deletion

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12 December 2020

Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

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12 December 2020

Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.

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12 December 2020

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

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12 December 2020

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

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12 December 2020

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

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12 December 2020

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

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12 December 2020

The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter

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12 December 2020

Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event

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12 December 2020

AIF deficiency compromises oxidative phosphorylation

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12 December 2020

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

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12 December 2020

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12 December 2020

Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA

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12 December 2020

Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention

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12 December 2020

Progressive accumulation of mitochondrial DNA mutations and decline in mitochondrial function lead to beta-cell failure

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12 December 2020

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

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12 December 2020

Mitochondrial DNA: does more lead to less?

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12 December 2020

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12 December 2020

A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.

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12 December 2020

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

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12 December 2020

New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome

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12 December 2020

On the role of uncoupling protein-2 in pancreatic beta cells.

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12 December 2020

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

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12 December 2020

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

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12 December 2020

Mitochondrial dysfunction in pancreatic beta-cells in Type 2 diabetes

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12 December 2020

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

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12 December 2020

Fat and beyond: the diverse biology of PPARgamma

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12 December 2020

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

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12 December 2020

Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle.

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12 December 2020

The variability of the harlequin mouse phenotype resembles that of human mitochondrial-complex I-deficiency syndromes

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12 December 2020

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

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12 December 2020

Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth

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12 December 2020

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction

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12 December 2020

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

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12 December 2020

Duplications of mitochondrial DNA in mitochondrial myopathy

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12 December 2020

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

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12 December 2020

Prevalence and progression of diabetes in mitochondrial disease

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12 December 2020

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

1 reference

12 December 2020

Type 2 diabetes: principles of pathogenesis and therapy

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12 December 2020

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

1 reference

12 December 2020

Mitochondrial dysfunction and type 2 diabetes

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12 December 2020

The ageing mitochondrial genome

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12 December 2020

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

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12 December 2020

10.1007/S10545-009-1263-0

Identifiers

DOI

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release_tdih6kq32bdbdcy52kwlmxqob4

21 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/tdih6kq32bdbdcy52kwlmxqob4

24 November 2022

mapped directly with Wikidata item

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