Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death (Q37842582)

24 August 2017

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title

Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death (English)

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24 August 2017

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Martin Chopra

1

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PubMed ID

21323611

24 August 2017

Dieter Schrenk

series ordinal

2

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PubMed ID

21323611

24 August 2017

language of work or name

English

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publication date

17 February 2011

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Critical Reviews in Toxicology

24 August 2017

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24 August 2017

41

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24 August 2017

4

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24 August 2017

292-320

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Protein kinase Ctheta activity is involved in the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line.

24 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Targeting the extrinsic apoptosis pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Death receptors: signaling and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

IGFBP-6 five years on; not so 'forgotten'?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Effects of TCDD on the fate of naive dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor complex and the control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Tetrachlorodibenzo-p-Dioxin (TCDD) Inhibits Differentiation and Increases Apoptotic Cell Death of Precursor T-Cells in the Fetal Mouse Thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or diethylstilbestrol (DES) cause similar hematopoietic hypocellularity and hepatocellular changes in murine fetal liver, but differentially affect gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Inhibition of apoptosis in rat hepatocytes treated with 'non-dioxin-like' polychlorinated biphenyls.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Comparative toxicogenomic analysis of the hepatotoxic effects of TCDD in Sprague Dawley rats and C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Enhanced activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity in peripheral T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces Fas-dependent activation-induced cell death in superantigen-primed T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Endocrine disruptor, dioxin (TCDD)-induced mitochondrial dysfunction and apoptosis in human trophoblast-like JAR cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Leukotriene A4 metabolites are endogenous ligands for the Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Inhibition of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Inhibition of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin depends on protein biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cell death: critical control points

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits growth factor withdrawal-induced apoptosis in the human mammary epithelial cell line, MCF-10A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor antagonist, 3'methoxy-4'nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced decrease in anti-CD3-activated CD4(+) T cells: the roles of apoptosis, Fas, and TNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Identification of necrotic cell death by the TUNEL assay in the hypoxic-ischemic neonatal rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Functional activation of arylhydrocarbon receptor (AhR) in primary T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induces apoptosis in the dorsal midbrain of zebrafish embryos by activation of arylhydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Alterations in the growth factor signal transduction pathways and modulators of the cell cycle in endocervical cells from macaques exposed to TCDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Many cuts to ruin: a comprehensive update of caspase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Aryl hydrocarbon receptor-dependent induction of loss of mitochondrial membrane potential in epididydimal spermatozoa by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-tetrachlorodibenzo-p-dioxin enhances negative selection of T cells in the thymus but allows autoreactive T cells to escape deletion and migrate to the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis and caspases in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Control of apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Early consequences of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on the activation and survival of antigen-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications for benzene-induced hematopoietic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Perinatal TCDD exposure and the adult onset of autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Toxic effects of TCDD on osteogenesis through altering IGFBP-6 gene expression in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The morphology of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis - the p53 network

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Modulation of ovarian follicle maturation and effects on apoptotic cell death in Holtzman rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in utero and lactationally.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

TCDD and a putative endogenous AhR ligand, ITE, elicit the same immediate changes in gene expression in mouse lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: possible mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cell death induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) in AtT-20 pituitary cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) by human cytochrome P450-dependent monooxygenase systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Neonatal exposure to low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin causes autoimmunity due to the disruption of T cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Molecular mechanisms of cytochrome p450 induction: potential for drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Overview of cell death signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Characterization of phenotypic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocytes in vivo and its effect on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cytochrome P450 gene regulation and physiological functions mediated by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Immunological effects of chlorinated dibenzo-p-dioxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Recent advances in understanding the mechanisms of TCDD immunotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

AHR-mediated immunomodulation: the role of altered gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Method for evaluation of immunotoxicity of dioxin compounds using human T-lymphoblastic cell line, L-MAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Upregulation of surface markers on dying thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Calcium/calmodulin signaling elicits release of cytochrome c during 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptosis in the human lymphoblastic T-cell line, L-MAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins: an expanded and updated international cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced activation of mitogen-activated protein kinase signaling pathway in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Ahr null alleles: distinctive or different?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Role of the aryl hydrocarbon receptor in the development of control and 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Treatment of normal human keratinocytes with 2,3,7,8-tetrachlorodibenzo-p-dioxin causes a reduction in cell number, but no increase in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation pattern of human keratinocytes in organotypic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cell Proliferation Arrest within Intrathymic Lymphocyte Progenitor Cells Causes Thymic Atrophy Mediated by the Aryl Hydrocarbon Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cancer mortality among workers in chemical plant contaminated with dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces insulin-like growth factor binding protein-1 gene expression and counteracts the negative effect of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis and cancer: the failure of controls on cell death and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Effects of dioxin, an environmental pollutant, on mouse blastocyst development and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

An IARC evaluation of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans as risk factors in human carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The extended protein kinase C superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Serum dioxin and immunologic response in veterans of Operation Ranch Hand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Regulation of insulin-like growth factor binding protein-1 and lipoprotein lipase by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Enhanced suppression of humoral immunity in DBA2 mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts B-cell lymphopoiesis and exacerbates autoimmune disease in 24-week-old SNF1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Constitutive activation of the aryl hydrocarbon receptor in T-lineage cells induces thymus involution independently of the Fas/Fas ligand signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Simultaneous in vivo time course and dose response evaluation for TCDD-induced impairment of the LPS-stimulated primary IgM response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Role of cAMP in mediating AHR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

TCDD activates Mdm2 and attenuates the p53 response to DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Aspects of dioxin toxicity are mediated by interleukin 1-like cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Dioxin-induced chloracne--reconstructing the cellular and molecular mechanisms of a classic environmental disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

TCDD-induced apoptosis in EL-4 cells deficient of the aryl hydrocarbon receptor and down-regulation of IGFBP-6 prevented the apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Cancer incidence in the population exposed to dioxin after the "Seveso accident": twenty years of follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Nuclear receptors: the controlling force in drug metabolism of the liver?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

p53 and E2f: partners in life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Ube2l3 gene expression is modulated by activation of the aryl hydrocarbon receptor: implications for p53 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Molecular mechanisms of apoptosis induced by cytotoxic chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8 Tetrachlorodibenzo-p-Dioxin (TCDD) Directly Enhances the Maturation and Apoptosis of Dendritic Cells In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Limitations of the toxic equivalency factor approach for risk assessment of TCDD and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Recognition and phagocytosis of cells undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Apoptosis in cancer--implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Ah receptor ligands and tumor promotion: survival of neoplastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Selection of the T cell repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Estimates of cancer potency of 2,3,7,8-tetrachlorodibenzo(p)dioxin using linear and nonlinear dose-response modeling and toxicokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Transcription-independent p53 apoptosis: an alternative route to death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Drug transporters: gatekeepers controlling access of xenobiotics to the cellular interior

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Chloracne, "the hallmark of dioxin intoxication"

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Ah receptor and NF-kappaB interplay on the stage of epigenome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

T Cell-Specific Disruption of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Gene Causes Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Thymic Involution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses apoptosis and leads to hyperphosphorylation of p53 in rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Role of NF-kappaB in the regulation of cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Protein Kinase C (PKC ): A Key Enzyme in T Cell Life and Death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

Human CD4+CD25+ Regulatory T Lymphocytes Inhibit Lipopolysaccharide-Induced Monocyte Survival through a Fas/Fas Ligand-Dependent Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2010.524635

10.3109/10408444.2010.524635

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21323611