NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia (Q37861191)

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scientific article published on 04 April 2011

Language	Label	Description	Also known as
English	NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia	scientific article published on 04 April 2011

Statements

scholarly article

1 reference

Europe PubMed Central

24 August 2017

1 reference

Europe PubMed Central

NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia (English)

1 reference

Europe PubMed Central

24 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Dongmei Guo

1

1 reference

Europe PubMed Central

24 August 2017

Qingliang Teng

2

1 reference

Europe PubMed Central

24 August 2017

Chunyan Ji

3

1 reference

Europe PubMed Central

24 August 2017

publication date

4 April 2011

1 reference

Europe PubMed Central

24 August 2017

Leukemia & Lymphoma

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Europe PubMed Central

24 August 2017

52

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Europe PubMed Central

24 August 2017

1200-1210

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Europe PubMed Central

24 August 2017

7

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Europe PubMed Central

24 August 2017

Notch signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Control points in early T-cell development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch signaling: cell fate control and signal integration in development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The ins and outs of notch signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch signaling: from the outside in

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch signalling: a simple pathway becomes complex

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Cell and molecular biology of Notch.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Signalling downstream of activated mammalian Notch

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

HERP, a new primary target of Notch regulated by ligand binding

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

MHC recognition in thymic development: distinct, parallel pathways for survival and lineage commitment.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Correlating notch signaling with thymocyte maturation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Direct regulation of the Nrarp gene promoter by the Notch signaling pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The nervous system and innate immunity: the neuropeptide connection

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch directly regulates Gata3 expression during T helper 2 cell differentiation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch inhibition of E47 supports the existence of a novel signaling pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch receptors and hematopoiesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch regulation of lymphocyte development and function.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

T-cell development, doing it in a dish.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Fine-tuning Notch1 activation by endocytosis and glycosylation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Akt-dependent transformation: there is more to growth than just surviving

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

AKT/PKB signaling: navigating downstream

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Conditional EGFR promotes cell cycle progression and prevention of apoptosis in the absence of autocrine cytokines

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The role of class I phosphoinositide 3-kinase in T-cell function and autoimmunity

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Enhanced T cell proliferation in mice lacking the p85beta subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The role of the PI3K-AKT kinase pathway in T-cell development beyond the beta checkpoint

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Interleukin-2 receptor downstream events in regulatory T cells: implications for the choice of immunosuppressive drug therapy

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Antigen receptor regulation of phosphoinositide-dependent kinase 1 pathways during thymocyte development.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Activating Notch1 mutations in mouse models of T-ALL.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Multiple niches for Notch in cancer: context is everything

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Recent insights into the role of Notch signaling in tumorigenesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The Akt-mTOR tango and its relevance to cancer

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

PTEN expression is a strong predictor of survival in mesothelioma patients

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Induction of Akt activity by chemotherapy confers acquired resistance

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Targeting the Notch1 and mTOR pathways in a mouse T-ALL model

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

PTEN: from pathology to biology

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Glycogen synthase kinase-3beta modulates notch signaling and stability

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Notch1 is an effector of Akt and hypoxia in melanoma development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Chromosome abnormalities in advanced stage lymphoblastic lymphoma of children and adolescents: a report from CCG-E08.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells In Vitro

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2011.564696

21 January 2018

Identifiers

10.3109/10428194.2011.564696

1 reference

Europe PubMed Central

24 August 2017

1 reference

Europe PubMed Central

24 August 2017

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