Subcellular fate and off-target effects of siRNA, shRNA, and miRNA. (Q37950261)

25 August 2017

Subcellular fate and off-target effects of siRNA, shRNA, and miRNA. (English)

1 reference

25 August 2017

Saurabh Singh

1

1 reference

25 August 2017

Ajit S Narang

series ordinal

2

1 reference

25 August 2017

Ram I Mahato

series ordinal

3

1 reference

25 August 2017

language of work or name

1 reference

28 October 2011

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25 August 2017

Pharmaceutical Research

1 reference

25 August 2017

28

1 reference

25 August 2017

12

1 reference

25 August 2017

2996-3015

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

25 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Heritable gene silencing in Drosophila using double-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Double-stranded RNA injection produces null phenotypes in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNAi in mouse oocytes and preimplantation embryos: effectiveness of hairpin dsRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNA interference and small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A two step model aimed at delivering antisense oligonucleotides in targeted cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Sequence-specific triple helix formation with genomic DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Biodistribution and hepatic uptake of triplex-forming oligonucleotides against type alpha1(I) collagen gene promoter in normal and fibrotic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Triplex forming oligonucleotides against type α1(I) collagen attenuates liver fibrosis induced by bile duct ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Immune responses to dsRNA: implications for gene silencing technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Efficient and targeted delivery of siRNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Short interfering RNA (siRNA) as a novel therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Current prospects for RNA interference-based therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Ribo-gnome: the big world of small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Approaches for chemically synthesized siRNA and vector-mediated RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Interfering with disease: a progress report on siRNA-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Structural insights into RNA processing by the human RISC-loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Phylogenetic shadowing and computational identification of human microRNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNAs: a new class of gene regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Detection of microRNAs in dried serum blots

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNAi-based treatment for neovascular age-related macular degeneration by Sirna-027.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Galactose-modified cationic liposomes as a liver-targeting delivery system for small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Tumor regression in mice by delivery of Bcl-2 small interfering RNA with pegylated cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Factors and mechanism of "EPR" effect and the enhanced antitumor effects of macromolecular drugs including SMANCS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Extracellular matrix glycoproteins and diffusion barriers in human astrocytic tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Single-particle tracking as a quantitative microscopy-based approach to unravel cell entry mechanisms of viruses and pharmaceutical nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Surveillance of siRNA integrity by FRET imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Intracellular distribution of microinjected antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

siRNA in human cells selectively localizes to target RNA sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

An Argonaute transports siRNAs from the cytoplasm to the nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Stable suppression of gene expression by RNAi in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Exportin-5 mediates nuclear export of minihelix-containing RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

RNAi in human cells: basic structural and functional features of small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

The RNA silencing pathway: the bits and pieces that matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Mathematical models of RNA silencing: unidirectional amplification limits accidental self-directed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Dynamics of gene silencing by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Long-lasting RNAi activity in mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

In vivo activity of nuclease-resistant siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

In situ analysis of single-stranded and duplex siRNA integrity in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

siRNA-like double-stranded RNAs are specifically protected against degradation in human cell extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Analysis of gene function in somatic mammalian cells using small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Stable knockdown of MYCN by lentivirus-based RNAi inhibits human neuroblastoma cells growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Minimizing the risk of reporting false positives in large-scale RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Determinants of targeting by endogenous and exogenous microRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNA-like off-target transcript regulation by siRNAs is species specific.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Sequence determinants of innate immune activation by short interfering RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Activation of the mammalian immune system by siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Overcoming the innate immune response to small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Improving siRNA bio-distribution and minimizing side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Pre-mRNA secondary structures influence exon recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Defining the optimal parameters for hairpin-based knockdown constructs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A microRNA embedded AAV α-synuclein gene silencing vector for dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Bipartite vectors for co-expression of a growth factor cDNA and short hairpin RNA against an apoptotic gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Modifying the specificity of an RNA backbone contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Cationic lipids with increased DNA binding affinity for nonviral gene transfer in dividing and nondividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Breaking up the correlation between efficacy and toxicity for nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Visualization of the degradation of a disulfide polymer, linear poly(ethylenimine sulfide), for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Reducible poly(amido ethylenimine) directed to enhance RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A novel environment-sensitive biodegradable polydisulfide with protonatable pendants for nucleic acid delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Delivery of siRNA mediated by histidine-containing reducible polycations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Cellular siRNA delivery using cell-penetrating peptides modified for endosomal escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Delivery of therapeutic shRNA and siRNA by Tat fusion peptide targeting BCR-ABL fusion gene in Chronic Myeloid Leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

PEI-g-PEG-RGD/small interference RNA polyplex-mediated silencing of vascular endothelial growth factor receptor and its potential as an anti-angiogenic tumor therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Targeted gene silencing using RGD-labeled chitosan nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Structural and formulation factors influencing pyridinium lipid-based gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

MicroRNA-133 controls cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

PE38KDEL-loaded anti-HER2 nanoparticles inhibit breast tumor progression with reduced toxicity and immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0608-1

Targeted delivery of SiRNA to CD33-positive tumor cells with liposomal carrier systems

21 January 2018

1 reference

12 December 2020

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

1 reference

12 December 2020

In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs.

1 reference

12 December 2020

Targeted gene silencing of TLR4 using liposomal nanoparticles for preventing liver ischemia reperfusion injury.

1 reference

12 December 2020

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

12 December 2020

Humanized Lewis-Y specific antibody based delivery of STAT3 siRNA.

1 reference

12 December 2020

MicroRNAs and lung cancer: Biology and applications in diagnosis and prognosis.

1 reference

12 December 2020

Aberrant expression of let-7a miRNA in the blood of non-small cell lung cancer patients

1 reference

12 December 2020

FRET-based probing to gain direct information on siRNA sustainability in live cells: Asymmetric degradation of siRNA strands

1 reference

12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

12 December 2020

Fusogenic peptides enhance endosomal escape improving siRNA-induced silencing of oncogenes

1 reference

12 December 2020

Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

1 reference

12 December 2020

Direct CNS delivery of siRNA mediates robust silencing in oligodendrocytes

1 reference

12 December 2020

A folate receptor-targeting nanoparticle minimizes drug resistance in a human cancer model.

1 reference

12 December 2020

Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery

1 reference

12 December 2020

Effect of lentivirus-mediated shRNA targeting VEGFR-3 on proliferation, apoptosis and invasion of gastric cancer cells

1 reference

12 December 2020

10.1007/S11095-011-0608-1

Identifiers

DOI

1 reference

25 August 2017

1 reference