It takes two to tango: IκBs, the multifunctional partners of NF-κB. (Q37995679)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

It takes two to tango: IκBs, the multifunctional partners of NF-κB (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Seda Çöl Arslan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Claus Scheidereit

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

published in

Immunological Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

59-76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Mutations in the NF-kappaB signaling pathway: implications for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Shared principles in NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation and function of NF-kappaB transcription factors in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Ubiquitination and degradation of the inhibitors of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cloning and functional characterization of mouse IkappaBepsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A novel IkappaB protein, IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBeta, a nuclear IkappaB protein, positively regulates the NF-kappaB-mediated expression of proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The noncanonical NF-κB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Early evolution of metazoan transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-κB: where did it come from and why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB in the immune response of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Rel homology domain-containing transcription factors in the cnidarian Nematostella vectensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Evidence for the ancient origin of the NF-kappaB/IkappaB cascade: its archaic role in pathogen infection and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Characterization of the core elements of the NF-κB signaling pathway of the sea anemone Nematostella vectensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A structural guide to proteins of the NF-kappaB signaling module

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Ankyrin repeat: a unique motif mediating protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Structural studies of NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBbeta is an essential co-activator for LPS-induced IL-1beta transcription in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Distinct functional properties of IkappaB alpha and IkappaB beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Alternative splicing variants of IkappaB beta establish differential NF-kappaB signal responsiveness in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Structure of an IkappaBalpha/NF-kappaB complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of IkappaBbeta expression in testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

RelA/p65 regulation of IkappaBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of IkappaB beta in WEHI 231 mature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Characterization of the nuclear import and export functions of Ikappa B(epsilon).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The precursor of NF-kappa B p50 has I kappa B-like functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Structural and functional characterization of the promoter regions of the NFKB2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of naive T cell function by the NF-kappaB2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A fourth IkappaB protein within the NF-kappaB signaling module

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

RelB cellular regulation and transcriptional activity are regulated by p100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Modulation of NF-kappaB activity by exchange of dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

New regulators of NF-kappaB in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappaB homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Diverse effects of BCL3 phosphorylation on its modulation of NF-kappaB p52 homodimer binding to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of NF-κB by deubiquitinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A small-molecule inhibitor shows that pirin regulates migration of melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Requirement for NF-kappaB in osteoclast and B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The IκB family member Bcl-3 coordinates the pulmonary defense against Klebsiella pneumoniae infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Immunological defects in mice with a targeted disruption in Bcl-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A role for the IkappaB family member Bcl-3 in the control of central immunologic tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Positive and negative regulation of nuclear factor-kappaB-mediated transcription by IkappaB-zeta, an inducible nuclear protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Targeted disruption of MAIL, a nuclear IkappaB protein, leads to severe atopic dermatitis-like disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Gene-specific requirement of a nuclear protein, IkappaB-zeta, for promoter association of inflammatory transcription regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IκBζ augments IL-12- and IL-18-mediated IFN-γ production in human NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A novel role for IkappaBzeta in the regulation of IFNgamma production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The ankyrin repeat as molecular architecture for protein recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-κB regulation: lessons from structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Transcriptional regulation via the NF-kappaB signaling module.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Lessons from mathematically modeling the NF-κB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of NF-κB by ubiquitination and degradation of the IκBs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB dictates the degradation pathway of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Mechanism of direct degradation of IkappaBalpha by 20S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

MiR-125b targets BCL3 and suppresses ovarian cancer proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IkappaBzeta expression is regulated by miR-124a

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Inflammation meets cancer, with NF-κB as the matchmaker

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-κB addiction and its role in cancer: 'one size does not fit all'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-κB and the link between inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

NF-kappaB in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Variation in transcription factor binding among humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Combined deficiency in I B and I B reveals a critical window of NF- B activity in natural killer cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01102.X

10.1111/J.1600-065X.2012.01102.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435547%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference