AMP-activated protein kinase: new regulation, new roles? (Q38019034)

27 August 2017

AMP-activated protein kinase: new regulation, new roles? (English)

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27 August 2017

David Carling

1

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27 August 2017

Claire Thornton

series ordinal

2

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27 August 2017

Angela Woods

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3

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27 August 2017

Matthew J Sanders

series ordinal

4

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27 August 2017

language of work or name

English

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publication date

1 July 2012

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27 August 2017

17

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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27 August 2017

445

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27 August 2017

11-27

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27 August 2017

1

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AMP-activated protein kinase: also regulated by ADP?

27 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK: a metabolic gauge regulating whole-body energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK in Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK inhibition in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK: an emerging drug target for diabetes and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The AMP-activated protein kinase cascade--a unifying system for energy control

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK beta subunit targets metabolic stress sensing to glycogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The structure of a domain common to archaebacteria and the homocystinuria disease protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Glucose repression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The regulation of AMP-activated protein kinase by upstream kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Ppm1E is an in cellulo AMP-activated protein kinase phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Requirements for calcium and calmodulin in the calmodulin kinase activation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Structure of mammalian AMPK and its regulation by ADP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK is a direct adenylate charge-regulated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Structural basis for AMP binding to mammalian AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK structure and regulation from three angles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase: nature's energy sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Structural insight into the autoinhibition mechanism of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A fluorescent reporter of AMPK activity and cellular energy stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Autophagy and the integrated stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Atg101, a novel mammalian autophagy protein interacting with Atg13

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Phagocytosis of Histoplasma capsulatum yeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase plays a role in the control of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Drosophila alicorn is a neuronal maintenance factor protecting against activity-induced retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABAB receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Early alterations of brain cellular energy homeostasis in Huntington disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The regulation and function of mammalian AMPK-related kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

mTOR signaling in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Genome-wide survey of protein kinases required for cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Metformin and reduced risk of cancer in diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Obesity and insulin resistance in breast cancer--chemoprevention strategies with a focus on metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase promotes human prostate cancer cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Down-regulation of AMP-activated protein kinase sensitizes DU145 carcinoma to Fas-induced apoptosis via c-FLIP degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Myosin phosphatase: structure, regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Regulation of myosin II during cytokinesis in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Energy-dependent regulation of cell structure by AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

AMP-activated protein kinase modulators: a patent review (2006 - 2010).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Effects of trans- and cis-resveratrol on Ca2+ handling in A7r5 vascular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The role of ATM in response to metformin treatment and activation of AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Calorie restriction and resveratrol in cardiovascular health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Sensing of energy and nutrients by AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Development of novel adenosine monophosphate-activated protein kinase activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Targeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

A small molecule AMPK activator protects the heart against ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120546

21 January 2018

Identifiers

DOI

10.1042/BJ20120546

1 reference

27 August 2017

1 reference