The recognition and removal of cellular poly(ADP-ribose) signals. (Q38109700)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23711178%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

The recognition and removal of cellular poly(ADP-ribose) signals (English)

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1 March 2020

3

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1 March 2020

Ivan Ahel

4

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1 March 2020

author name string

Eva Barkauskaite

1

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1 March 2020

Gytis Jankevicius

2

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1 March 2020

Gyula Timinszky

5

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1 March 2020

language of work or name

English

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publication date

18 June 2013

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1 March 2020

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1 March 2020

volume

280

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1 March 2020

issue

15

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1 March 2020

page(s)

3491-3507

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New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

1 March 2020

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Random mutagenesis of the poly(ADP-ribose) polymerase catalytic domain reveals amino acids involved in polymer branching.

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Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase

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A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

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Poly(ADP-ribose) binds to the splicing factor ASF/SF2 and regulates its phosphorylation by DNA topoisomerase I.

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Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

21 January 2018

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21 January 2018

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21 January 2018

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Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response

21 January 2018

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21 January 2018

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Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR)

21 January 2018

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APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks

21 January 2018

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PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks

21 January 2018

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APLF promotes the assembly and activity of non-homologous end joining protein complexes

21 January 2018

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CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation

21 January 2018

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21 January 2018

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RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

21 January 2018

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Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

21 January 2018

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Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

21 January 2018

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Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination

21 January 2018

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21 January 2018

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Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase.

21 January 2018

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Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

21 January 2018

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Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

21 January 2018

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ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose).

21 January 2018

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A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

21 January 2018

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PARP is involved in replicative aging in Neurospora crassa

21 January 2018

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Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA

21 January 2018

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Altered DNA damage response in Caenorhabditis elegans with impaired poly(ADP-ribose) glycohydrolases genes expression

21 January 2018

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Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain

21 January 2018

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Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase

21 January 2018

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Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element

21 January 2018

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Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives

21 January 2018

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PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.

21 January 2018

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Identification of an Inhibitor Binding Site of Poly(ADP-ribose) Glycohydrolase

21 January 2018

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Large-scale preparation and characterization of poly(ADP-ribose) and defined length polymers

21 January 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

21 January 2018

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Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

21 January 2018

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MNNG-induced cell death is controlled by interactions between PARP-1, poly(ADP-ribose) glycohydrolase, and XRCC1.

21 January 2018

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Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells

21 January 2018

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Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

21 January 2018

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Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

21 January 2018

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PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion

21 January 2018

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Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury

21 January 2018

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Poly(ADP-ribose): PARadigms and PARadoxes

21 January 2018

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Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice

21 January 2018

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Selective small molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG).

21 January 2018

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The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation

21 January 2018

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Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix

21 January 2018

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The 39-kDa poly(ADP-ribose) glycohydrolase ARH3 hydrolyzes O-acetyl-ADP-ribose, a product of the Sir2 family of acetyl-histone deacetylases

21 January 2018

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Estrogenically regulated LRP16 interacts with estrogen receptor alpha and enhances the receptor's transcriptional activity

21 January 2018

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The single-macro domain protein LRP16 is an essential cofactor of androgen receptor

21 January 2018

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The C20orf133 gene is disrupted in a patient with Kabuki syndrome

21 January 2018

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The C20orf133 gene is disrupted in a patient with Kabuki syndrome

21 January 2018

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ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation.

21 January 2018

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Poly(ADP-ribose) (PAR) polymer is a death signal

21 January 2018

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

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Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

21 January 2018

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Histone macroH2A isoforms predict the risk of lung cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12358