Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases (Q38195215)

30 August 2017

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title

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases (English)

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30 August 2017

endoplasmic reticulum

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Claudio Hetz

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

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publication date

12 March 2014

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Nature Reviews Neuroscience

30 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

233-249

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619348%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrn3689

9 June 2020

exact match

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cites work

Adapting proteostasis for disease intervention

1 reference

Molecular chaperones in protein folding and proteostasis

21 January 2018

1 reference

Protein folding and modification in the mammalian endoplasmic reticulum.

21 January 2018

1 reference

The unfolded protein response: from stress pathway to homeostatic regulation

21 January 2018

1 reference

The impact of the unfolded protein response on human disease

21 January 2018

1 reference

The unfolded protein response: integrating stress signals through the stress sensor IRE1α

21 January 2018

1 reference

Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments

21 January 2018

1 reference

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

1 reference

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

21 January 2018

1 reference

Signaling cell death from the endoplasmic reticulum stress response

21 January 2018

1 reference

When ER stress reaches a dead end

21 January 2018

1 reference

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

21 January 2018

1 reference

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

Unfolding the role of protein misfolding in neurodegenerative diseases

21 January 2018

1 reference

Folding proteins in fatal ways

21 January 2018

1 reference

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

Recent advances in the genetics of Parkinson's disease

21 January 2018

1 reference

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

21 January 2018

1 reference

Protein aggregates in Huntington's disease.

21 January 2018

1 reference

21 January 2018

1 reference

Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis

21 January 2018

1 reference

Endoplasmic reticulum dysfunction in neurological disease

21 January 2018

1 reference

An ERcentric view of Parkinson's disease

21 January 2018

1 reference

ER Dysfunction and Protein Folding Stress in ALS.

21 January 2018

1 reference

Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's disease

21 January 2018

1 reference

Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells

21 January 2018

1 reference

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

21 January 2018

1 reference

ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's disease

21 January 2018

1 reference

The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death

21 January 2018

1 reference

Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease.

21 January 2018

1 reference

Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo

21 January 2018

1 reference

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

1 reference

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

21 January 2018

1 reference

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

21 January 2018

1 reference

The unfolded protein response in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis

21 January 2018

1 reference

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice

21 January 2018

1 reference

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

21 January 2018

1 reference

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

21 January 2018

1 reference

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

21 January 2018

1 reference

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

21 January 2018

1 reference

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

21 January 2018

1 reference

The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

1 reference

Transmissible proteins: expanding the prion heresy

21 January 2018

1 reference

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

21 January 2018

1 reference

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

21 January 2018

1 reference

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

21 January 2018

1 reference

Prion pathogenesis is independent of caspase-12.

21 January 2018

1 reference

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

21 January 2018

1 reference

The unfolded protein response in Alzheimer's disease

21 January 2018

1 reference

The ER stress factor XBP1s prevents amyloid-beta neurotoxicity

21 January 2018

1 reference

JNK3 perpetuates metabolic stress induced by Aβ peptides.

21 January 2018

1 reference

The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans

21 January 2018

1 reference

Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

21 January 2018

1 reference

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

21 January 2018

1 reference

ER stress protects from retinal degeneration

21 January 2018

1 reference

Unfolded protein response in a Drosophila model for retinal degeneration

21 January 2018

1 reference

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

21 January 2018

1 reference

Activation of the unfolded protein response enhances motor recovery after spinal cord injury

21 January 2018

1 reference

Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury

21 January 2018

1 reference

Attenuating the endoplasmic reticulum stress response improves functional recovery after spinal cord injury

21 January 2018

1 reference

Deletion of the pro-apoptotic endoplasmic reticulum stress response effector CHOP does not result in improved locomotor function after severe contusive spinal cord injury

21 January 2018

1 reference

Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.

21 January 2018

1 reference

Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain

21 January 2018

1 reference

A molecular chaperone inducer protects neurons from ER stress

21 January 2018

1 reference

InterfERing with endoplasmic reticulum stress

21 January 2018

1 reference

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

21 January 2018

1 reference

Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress

21 January 2018

1 reference

Endoplasmic reticulum stress in disorders of myelinating cells.

21 January 2018

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Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress.

21 January 2018

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Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma

21 January 2018

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The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

21 January 2018

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Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis

21 January 2018

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The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

21 January 2018

1 reference

Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice

21 January 2018

1 reference

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

21 January 2018

1 reference

The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling

21 January 2018

1 reference

Targeting endoplasmic reticulum stress in metabolic disease

21 January 2018

1 reference

The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction

21 January 2018

1 reference

ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones.

21 January 2018

1 reference

Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL

21 January 2018

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GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis

21 January 2018

1 reference

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

21 January 2018

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

Endoplasmic reticulum stress and prion diseases

21 January 2018

1 reference

Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death

21 January 2018

1 reference

ER stress in retinal degeneration: a target for rational therapy?

21 January 2018

1 reference

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

21 January 2018

1 reference

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease.

21 January 2018

1 reference

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

21 January 2018

1 reference

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

21 January 2018

1 reference

The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS.

21 January 2018

1 reference

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.

21 January 2018

1 reference

ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation

21 January 2018

1 reference

Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

21 January 2018

1 reference

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

21 January 2018

1 reference

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

21 January 2018

1 reference

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

21 January 2018

1 reference

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

21 January 2018

1 reference

Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.

21 January 2018

1 reference

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

21 January 2018

1 reference

Multisubunit tethering complexes and their role in membrane fusion

21 January 2018

1 reference

The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

21 January 2018

1 reference

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

21 January 2018

1 reference

Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs

21 January 2018

1 reference

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

21 January 2018

1 reference

The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites

21 January 2018

1 reference

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.

21 January 2018

1 reference

siRNA-mediated inhibition of endogenous Huntington disease gene expression induces an aberrant configuration of the ER network in vitro

21 January 2018

1 reference

Polymorphism -116C/G of human X-box-binding protein 1 promoter is associated with risk of Alzheimer's disease

21 January 2018

1 reference

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

21 January 2018

1 reference

Association studies indicate that protein disulfide isomerase is a risk factor in amyotrophic lateral sclerosis.

21 January 2018

1 reference

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

21 January 2018

1 reference

Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology

21 January 2018

1 reference

VAPB interacts with and modulates the activity of ATF6.

21 January 2018

1 reference

Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease.

21 January 2018

1 reference

Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

21 January 2018

1 reference

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

21 January 2018

1 reference

Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans

21 January 2018

1 reference

Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth

21 January 2018

1 reference

A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response

21 January 2018

1 reference

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

21 January 2018

1 reference

Mechanism of ER stress-induced brain damage by IP(3) receptor

21 January 2018

1 reference

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

21 January 2018

1 reference

The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins

21 January 2018

1 reference

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

21 January 2018

1 reference

Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis.

21 January 2018

1 reference

Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress

21 January 2018

1 reference

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

21 January 2018

1 reference

Altered subcellular distribution of the Alzheimer's amyloid precursor protein under stress conditions.

21 January 2018

1 reference

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

21 January 2018

1 reference

Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis

21 January 2018

1 reference

ATF4 regulates gamma-secretase activity during amino acid imbalance.

21 January 2018

1 reference

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

21 January 2018

1 reference

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.

21 January 2018

1 reference

21 January 2018

1 reference

Hormesis: its impact on medicine and health

21 January 2018

1 reference

Hormesis: protecting neurons against cellular stress in Parkinson disease

21 January 2018

1 reference

Establishing links between endoplasmic reticulum-mediated hormesis and cancer.

21 January 2018

1 reference

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

Redox signaling loops in the unfolded protein response

21 January 2018

1 reference

ER stress inhibits neuronal death by promoting autophagy

21 January 2018

1 reference

Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila

21 January 2018

1 reference

Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery

21 January 2018

1 reference

Translational control of long-lasting synaptic plasticity and memory

21 January 2018

1 reference

eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory

21 January 2018

1 reference

Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2

21 January 2018

1 reference

Suppression of PKR promotes network excitability and enhanced cognition by interferon-γ-mediated disinhibition

21 January 2018

1 reference

Blocking the eIF2α kinase (PKR) enhances positive and negative forms of cortex-dependent taste memory.

21 January 2018

1 reference

Pharmacological brake-release of mRNA translation enhances cognitive memory

21 January 2018

1 reference

Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.

21 January 2018

1 reference

Effects of environmental enrichment on gene expression in the brain

21 January 2018

1 reference

Cage food location alters energy balance and endoplasmic reticulum stress in the brain of mice.

21 January 2018

1 reference

Three weeks voluntary running wheel exercise increases endoplasmic reticulum stress in the brain of mice.

21 January 2018

1 reference

Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain

21 January 2018

1 reference

The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.

21 January 2018

1 reference

Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1.

21 January 2018

1 reference

The unfolded protein response regulates glutamate receptor export from the endoplasmic reticulum

21 January 2018

1 reference

Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila

21 January 2018

1 reference

Behavioral and gene expression analyses in heterozygous XBP1 knockout mice: Possible contribution of chromosome 11qA1 locus to prepulse inhibition.

21 January 2018

1 reference

Drosophila fatty acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival.

21 January 2018

1 reference

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

21 January 2018

1 reference

Endoplasmic reticulum stress plays a central role in development of leptin resistance

21 January 2018

1 reference

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.

21 January 2018

1 reference

Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways.

21 January 2018

1 reference

Salubrinal, an endoplasmic reticulum stress blocker, modulates sleep homeostasis and activation of sleep- and wake-regulatory neurons

21 January 2018

1 reference

Cell-nonautonomous control of the UPR.

21 January 2018

1 reference

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

21 January 2018

1 reference

Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation

21 January 2018

1 reference

XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity

21 January 2018

1 reference

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

21 January 2018

1 reference

Regulation of organismal proteostasis by transcellular chaperone signaling

21 January 2018

1 reference

Regulation of basal cellular physiology by the homeostatic unfolded protein response

21 January 2018

1 reference

Role of the unfolded protein response in organ physiology: lessons from mouse models.

21 January 2018

1 reference

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

21 January 2018

1 reference

Targeting the unfolded protein response in disease.

21 January 2018

1 reference

Endoplasmic reticulum: the unfolded protein response is tangled in neurodegeneration.

21 January 2018

1 reference

Protein disulfide isomerase-immunopositive inclusions in patients with Alzheimer disease.

21 January 2018

1 reference

Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease.

21 January 2018

1 reference

The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

21 January 2018

1 reference

Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology

21 January 2018

1 reference

Activation of the unfolded protein response in Parkinson's disease.

21 January 2018

1 reference

Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease

21 January 2018

1 reference

Protective effect against Parkinson's disease-related insults through the activation of XBP1

21 January 2018

1 reference

AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease

21 January 2018

1 reference

Ablation of C/EBP homologous protein does not protect T17M RHO mice from retinal degeneration

21 January 2018

1 reference

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

21 January 2018

1 reference

The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis

31 March 2020

1 reference

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

31 March 2020

1 reference

C/EBP homologous protein (CHOP) mediates neuronal apoptosis in rats with spinal cord injury

31 March 2020

1 reference

GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis

31 March 2020

1 reference

The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control

31 March 2020

1 reference

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

31 March 2020

1 reference

Endoplasmic reticulum stress enhances γ-secretase activity

31 March 2020

1 reference

Clinical application of remote ischemic preconditioning

31 March 2020

1 reference

Cardioprotection by endoplasmic reticulum stress-induced autophagy

31 March 2020

1 reference

XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy

31 March 2020

1 reference

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

31 March 2020

1 reference

Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice

31 March 2020

1 reference

Endoplasmic reticulum stress in motor neurons of the spinal cord in sporadic amyotrophic lateral sclerosis

31 March 2020

1 reference

Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo

31 March 2020

1 reference

Memory loss in Alzheimer's disease: are the alterations in the UPR network involved in the cognitive impairment?

31 March 2020

1 reference

12 December 2020

Endoplasmic-reticulum calcium depletion and disease

1 reference

12 December 2020

Homocysteine-induced endoplasmic reticulum protein (herp) is up-regulated in parkinsonian substantia nigra and present in the core of Lewy bodies

1 reference

12 December 2020

Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

1 reference

12 December 2020

Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease

1 reference

12 December 2020