Microbial DNA recognition by cGAS-STING and other sensors in dendritic cells in inflammatory bowel diseases (Q38315636)

2 September 2017

1 reference

title

Microbial DNA recognition by cGAS-STING and other sensors in dendritic cells in inflammatory bowel diseases (English)

1 reference

inflammatory bowel diseases

2 September 2017

main subject

0 references

1 reference

Song Liu

1

1 reference

2 September 2017

Ying Zhang

series ordinal

2

1 reference

2 September 2017

Jianan Ren

series ordinal

3

1 reference

2 September 2017

Jieshou Li

series ordinal

4

1 reference

2 September 2017

language of work or name

1 reference

1 April 2015

1 reference

Inflammatory Bowel Diseases

2 September 2017

published in

1 reference

2 September 2017

volume

21

1 reference

2 September 2017

issue

4

1 reference

2 September 2017

page(s)

901-911

1 reference

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice.

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Intestinal lamina propria dendritic cell subsets have different origin and functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Origin of the lamina propria dendritic cell network

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

A new subset of CD103+CD8alpha+ dendritic cells in the small intestine expresses TLR3, TLR7, and TLR9 and induces Th1 response and CTL activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

ATP drives lamina propria T(H)17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Innate immune detection of microbial nucleic acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING recognition of cytoplasmic DNA instigates cellular defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING is a direct innate immune sensor of cyclic di-GMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Species-specific detection of the antiviral small-molecule compound CMA by STING

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING-dependent cytosolic DNA sensing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Bacterial c-di-GMP is an immunostimulatory molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Innate sensing of bacterial cyclic dinucleotides: more than just STING.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The mammalian PYHIN gene family: phylogeny, evolution and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cytosolic DNA-activated human dendritic cells are potent activators of the adaptive immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IFN-β expression is directly activated in human neutrophils transfected with plasmid DNA and is further increased via TLR-4-mediated signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

TLR9 as a key receptor for the recognition of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Self double-stranded (ds)DNA induces IL-1β production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

STRING 8--a global view on proteins and their functional interactions in 630 organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000299

10.1097/MIB.0000000000000299

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference