Innate immunity against HIV-1 infection (Q38491184)

3 September 2017

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title

Innate immunity against HIV-1 infection (English)

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3 September 2017

2

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3 September 2017

1

Marcus Altfeld

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PubMed ID

25988887

3 September 2017

language of work or name

English

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publication date

1 June 2015

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3 September 2017

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3 September 2017

16

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3 September 2017

554-562

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3 September 2017

6

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Innate antiviral immune signaling, viral evasion and modulation by HIV-1.

3 September 2017

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Antiviral innate immunity: editorial overview.

21 January 2018

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HIV-1 accessory proteins--ensuring viral survival in a hostile environment

21 January 2018

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Interactions between HIV-1 and the cell-autonomous innate immune system.

21 January 2018

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Unmasking immune sensing of retroviruses: interplay between innate sensors and host effectors

21 January 2018

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IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

21 January 2018

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Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

21 January 2018

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Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

21 January 2018

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

21 January 2018

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Interferon γ-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses

21 January 2018

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Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach

21 January 2018

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IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

21 January 2018

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Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.

21 January 2018

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Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

21 January 2018

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Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

21 January 2018

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

21 January 2018

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Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

21 January 2018

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The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.

21 January 2018

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Inhibition of HIV-1 disease progression by contemporaneous HIV-2 infection

21 January 2018

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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

21 January 2018

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

21 January 2018

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

21 January 2018

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Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

21 January 2018

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The interferon response to intracellular DNA: why so many receptors?

21 January 2018

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The enemy within: endogenous retroelements and autoimmune disease

21 January 2018

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The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

21 January 2018

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Toll-like receptors in antiviral innate immunity

21 January 2018

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HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

21 January 2018

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TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection.

21 January 2018

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Immune signaling by RIG-I-like receptors

21 January 2018

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RIG-I activation inhibits HIV replication in macrophages

21 January 2018

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Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

21 January 2018

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Antiviral activity of the interferon-induced cellular protein BST-2/tetherin

21 January 2018

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Tetherin inhibits HIV-1 release by directly tethering virions to cells

21 January 2018

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Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

21 January 2018

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Emerging role of the host restriction factor tetherin in viral immune sensing

21 January 2018

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Response of host inflammasomes to viral infection

21 January 2018

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HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes

21 January 2018

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HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon

21 January 2018

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

21 January 2018

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Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

21 January 2018

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The IFITM proteins inhibit HIV-1 infection

21 January 2018

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MX2 is an interferon-induced inhibitor of HIV-1 infection

21 January 2018

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The interferon-inducible MxB protein inhibits HIV-1 infection.

21 January 2018

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Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

21 January 2018

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Expression profile of host restriction factors in HIV-1 elite controllers

21 January 2018

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IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.

21 January 2018

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IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

21 January 2018

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Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins.

21 January 2018

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Structural insight into HIV-1 restriction by MxB.

21 January 2018

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Structural insights into interferon regulatory factor activation

21 January 2018

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Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells

21 January 2018

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HIV-1 Vpu does not degrade interferon regulatory factor 3.

21 January 2018

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HIV-1 Vpu accessory protein induces caspase-mediated cleavage of IRF3 transcription factor

21 January 2018

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Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism

21 January 2018

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HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

21 January 2018

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Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing

21 January 2018

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How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.

21 January 2018

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Vpu-deficient HIV strains stimulate innate immune signaling responses in target cells

21 January 2018

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Control of human viral infections by natural killer cells

21 January 2018

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Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

21 January 2018

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Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells

21 January 2018

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Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry

21 January 2018

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HLA/KIR restraint of HIV: surviving the fittest

21 January 2018

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HLA alleles determine differences in human natural killer cell responsiveness and potency

21 January 2018

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HIV protective KIR3DL1 and HLA-B genotypes influence NK cell function following stimulation with HLA-devoid cells

21 January 2018

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Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1*h/*y and HLA-B*57

21 January 2018

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HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets

21 January 2018

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Role of education and differentiation in determining the potential of natural killer cells to respond to antibody-dependent stimulation.

21 January 2018

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HIV infection abrogates the functional advantage of natural killer cells educated through KIR3DL1/HLA-Bw4 interactions to mediate anti-HIV antibody-dependent cellular cytotoxicity

21 January 2018

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Increased frequency and function of KIR2DL1-3⁺ NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.

21 January 2018

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Influence of HLA-C expression level on HIV control

21 January 2018

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The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

21 January 2018

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The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.

21 January 2018

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HIV-1 adaptation to NK-cell-mediated immune pressure

21 January 2018

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A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705.

21 January 2018

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Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

21 January 2018

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Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells

21 January 2018

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HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function

21 January 2018

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Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function

21 January 2018

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Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitope by CD8+ T cells and NK cells

21 January 2018

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Natural killer cells promote early CD8 T cell responses against cytomegalovirus

21 January 2018

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Innate immunity defines the capacity of antiviral T cells to limit persistent infection

21 January 2018

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NK cells regulating T cell responses: mechanisms and outcome

21 January 2018

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Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

21 January 2018

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IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

21 January 2018

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Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection

21 January 2018

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DCs and NK cells: critical effectors in the immune response to HIV-1.

21 January 2018

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Clinical course of primary HIV infection: consequences for subsequent course of infection

21 January 2018

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Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

21 January 2018

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Reprogramming human endothelial cells to haematopoietic cells requires vascular induction

21 January 2018

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Tumor necrosis factor α is associated with viral control and early disease progression in patients with HIV type 1 infection

21 January 2018

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Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection

21 January 2018

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Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina

21 January 2018

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NK and CD4+ T cell cooperative immune responses correlate with control of disease in a macaque simian immunodeficiency virus infection model

21 January 2018

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NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination

21 January 2018

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Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

21 January 2018

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Intrinsic host restrictions to HIV-1 and mechanisms of viral escape.

21 January 2018

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12 December 2020

Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology

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12 December 2020

T cell-dependent production of IFN-gamma by NK cells in response to influenza A virus

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12 December 2020

The impact of host genetic variation on infection with HIV-1.

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12 December 2020

Inflammasome-independent regulation of IL-1-family cytokines

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12 December 2020

Natural killer cells act as rheostats modulating antiviral T cells

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12 December 2020

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

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12 December 2020

Viral regulation and evasion of the host response.

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12 December 2020

Identifiers

DOI

10.1038/NI.3157

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3 September 2017

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PubMed ID

25988887