Targeting Inflammation in Cancer Prevention and Therapy (Q39027675)

8 January 2018

review article

1 reference

title

Targeting Inflammation in Cancer Prevention and Therapy (English)

1 reference

8 January 2018

1 reference

3

Michael Karin

1 reference

8 January 2018

Jelena Todoric

1

1 reference

8 January 2018

Laura Antonucci

series ordinal

2

1 reference

8 January 2018

publication date

10 November 2016

1 reference

8 January 2018

Cancer Prevention Research

published in

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8 January 2018

volume

9

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8 January 2018

issue

12

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8 January 2018

page(s)

895-905

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8 January 2018

Physical Activity and Cancer Outcomes: A Precision Medicine Approach

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The use of corticosteroids in patients with COPD or asthma does not decrease lung squamous cell carcinoma

17 June 2018

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Inflammation and cancer: advances and new agents

17 June 2018

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IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases.

17 June 2018

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Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin.

17 June 2018

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Current and future antiviral drug therapies of hepatitis B chronic infection

17 June 2018

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17 June 2018

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Liver fibrosis in alcoholic liver disease

17 June 2018

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Obesity as a cause of hepatocellular carcinoma

17 June 2018

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The interaction of anticancer therapies with tumor-associated macrophages

17 June 2018

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Macrophage recruitment in obese adipose tissue

17 June 2018

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Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.

17 June 2018

1 reference

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Global burden of cancer attributable to high body-mass index in 2012: a population-based study

17 June 2018

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Natural history of hepatitis C

17 June 2018

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Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models

17 June 2018

1 reference

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ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development

17 June 2018

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Tumor-associated macrophages as major players in the tumor microenvironment

17 June 2018

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Macrophages, immunity, and metabolic disease

17 June 2018

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Impact of myeloid cells on the efficacy of anticancer chemotherapy

17 June 2018

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Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

17 June 2018

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Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion

17 June 2018

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Microbes, microbiota, and colon cancer

17 June 2018

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17 June 2018

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Interactions between the intestinal microbiome and liver diseases

17 June 2018

1 reference

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Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control?

17 June 2018

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Immune cells: plastic players along colorectal cancer progression

17 June 2018

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Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates

17 June 2018

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STAT3 inhibitors for cancer therapy: Have all roads been explored?

17 June 2018

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Tissue-resident macrophages

17 June 2018

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17 June 2018

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The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer.

17 June 2018

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Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

17 June 2018

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Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis

17 June 2018

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Inflammasome in intestinal inflammation and cancer

17 June 2018

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Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice

17 June 2018

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Non-steroid anti-inflammatory drugs, prostaglandins, and cancer

17 June 2018

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The interplay between fiber and the intestinal microbiome in the inflammatory response

17 June 2018

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17 June 2018

Liver cancer and alcohol

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

17 June 2018

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17 June 2018

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17 June 2018

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Obesity, autophagy and the pathogenesis of liver and pancreatic cancers

17 June 2018

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17 June 2018

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Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer

17 June 2018

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How the risk of liver cancer changes after alcohol cessation: a review and meta-analysis of the current literature

17 June 2018

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Monocyte recruitment during infection and inflammation

17 June 2018

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Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies

17 June 2018

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Cigarette smoking and inflammation: cellular and molecular mechanisms

17 June 2018

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Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors

17 June 2018

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Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

17 June 2018

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

17 June 2018

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The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment

17 June 2018

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Projections of alcohol deaths--a wake-up call.

17 June 2018

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IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

17 June 2018

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Diet-induced weight loss reduces colorectal inflammation: implications for colorectal carcinogenesis

17 June 2018

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Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

17 June 2018

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Receptor for advanced glycation end-products signals through Ras during tobacco smoke-induced pulmonary inflammation.

17 June 2018

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COX-2 as a target for cancer chemotherapy

17 June 2018

1 reference

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Profiling in resolving inflammatory exudates identifies novel anti-inflammatory and pro-resolving mediators and signals for termination

17 June 2018

1 reference

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Macrophage diversity enhances tumor progression and metastasis

17 June 2018

1 reference

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Anti-Inflammatory Agents for Cancer Therapy

17 June 2018

1 reference

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Immunity, Inflammation, and Cancer

17 June 2018

1 reference

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Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation

17 June 2018

1 reference

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Inflammasome-mediated regulation of hepatic stellate cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe.

17 June 2018

1 reference

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Insulin and insulin-like growth factor signalling in neoplasia

17 June 2018

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Cancer-related inflammation

17 June 2018

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Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium

17 June 2018

1 reference

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NF-kappaB and epithelial to mesenchymal transition of cancer

17 June 2018

1 reference

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Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells.

17 June 2018

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Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

A cytokine-mediated link between innate immunity, inflammation, and cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Prebiotics: the concept revisited

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Inflammation and metabolic disorders

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Nuclear factor-kappaB in cancer development and progression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

The epidemiology of genital human papillomavirus infection

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Anti-inflammatory effects of statins: clinical evidence and basic mechanisms

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Statins and the risk of colorectal cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

The chemokine system in diverse forms of macrophage activation and polarization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Tumour-educated macrophages promote tumour progression and metastasis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

17 June 2018

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Helicobacter pylori and gastrointestinal tract adenocarcinomas

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Structural mechanism for statin inhibition of HMG-CoA reductase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Inflammation and cancer: back to Virchow?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

The primary and secondary prevention of cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

ras oncogenes in human cancer: a review

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Alcohol exacerbates LPS-induced fibrosis in subclinical acute pancreatitis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Targeting tumor-associated macrophages in an experimental glioma model with a recombinant immunotoxin to folate receptor beta

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

In memoriam of Rudolf virchow: a historical retrospective including aspects of inflammation, infection and neoplasia

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

The chemopreventive effects of orally administered dexamethasone in Strain A/J mice following cessation of smoke exposure

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Pretreatment with dexamethasone increases antitumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: in vivo activity, pharmacokinetics, and clinical implications for cancer chemotherapy

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Nitric oxide and oxygen radicals in infection, inflammation, and cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Carfilzomib, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142754

Reflections from the Dean's office

2 December 2018

1 reference

12 December 2020

Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids

1 reference

12 December 2020

Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells

1 reference

12 December 2020

Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis

1 reference

12 December 2020

EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease

1 reference

12 December 2020

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

12 December 2020

Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients

1 reference

12 December 2020

1 reference

12 December 2020

Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial

1 reference

12 December 2020

Management of alcohol use disorders in patients with chronic pancreatitis

1 reference

12 December 2020

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps

1 reference

12 December 2020

10.1158/1940-6207.CAPR-16-0209

Identifiers

DOI

1 reference

8 January 2018

PMC publication ID

5142754

1 reference

8 January 2018

PubMed publication ID

27913448

1 reference

8 January 2018