Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation (Q40573463)

21 September 2017

Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation (English)

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21 September 2017

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Ming-Tsan Lin

1

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21 September 2017

Cheng-Chi Chang

2

1 reference

21 September 2017

Szu-Ta Chen

3

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21 September 2017

Huei-Ling Chang

4

1 reference

21 September 2017

Jen-Liang Su

5

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21 September 2017

Yat-Pang Chau

6

1 reference

21 September 2017

Min-Liang Kuo

7

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21 September 2017

language of work or name

English

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publication date

24 March 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

23

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21 September 2017

24015-24023

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Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

21 September 2017

1 reference

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To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

21 January 2018

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CD105 prevents apoptosis in hypoxic endothelial cells

21 January 2018

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The 14-3-3 cancer connection

21 January 2018

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AP-1: a double-edged sword in tumorigenesis

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

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21 January 2018

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Apoptosis and melanoma chemoresistance

21 January 2018

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Cell cycle deregulation in B-cell lymphomas.

21 January 2018

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A multigenic program mediating breast cancer metastasis to bone

21 January 2018

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Cyr61 promotes breast tumorigenesis and cancer progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M402305200

CYR61 (CCN1) is essential for placental development and vascular integrity

21 January 2018

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CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family

21 January 2018

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Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily

21 January 2018

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Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

21 January 2018

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The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

21 January 2018

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The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts

21 January 2018

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Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61)

21 January 2018

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NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR‐α‐dependent mechanism

21 January 2018

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Glucocorticoid-attenuated response genes encode intercellular mediators, including a new C-X-C chemokine

21 January 2018

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Human CYR61-mediated enhancement of bFGF-induced DNA synthesis in human umbilical vein endothelial cells

21 January 2018

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Expression of the extracellular matrix signaling molecule Cyr61 is downregulated in prostate cancer.

21 January 2018

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Expression of cyr61, a growth factor-inducible immediate-early gene

21 January 2018

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Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

21 January 2018

1 reference

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Expression and regulation of Cyr61 in human breast cancer cell lines

21 January 2018

1 reference

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Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

1 reference

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The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

21 January 2018

1 reference

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Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

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Pinning NF-kappaB to the nucleus

21 January 2018

1 reference

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Apoptotic Action of 17 -Estradiol in Raloxifene-Resistant MCF-7 Cells In Vitro and In Vivo

21 January 2018

1 reference

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Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation

21 January 2018

1 reference

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Tyrosine Kinase p56 Regulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of IκBα following Hypoxia/Reoxygenation

21 January 2018

1 reference

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Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence

21 January 2018

1 reference

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Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells

21 January 2018

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Osteopontin stimulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through phosphatidylinositol 3-kinase/Akt signaling pathways in breast cancer cells

21 January 2018

1 reference

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BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit

21 January 2018

1 reference

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Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3'-kinase activity in breast cancer cells

21 January 2018

1 reference

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Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway

21 January 2018

1 reference

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Identification of a Novel Integrin αMβ2 Binding Site in CCN1 (CYR61), a Matricellular Protein Expressed in Healing Wounds and Atherosclerotic Lesions

21 January 2018

1 reference

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Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402305200

The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

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CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402305200

Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402305200

Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

21 January 2018

1 reference

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Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

21 January 2018

1 reference

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Expression of ErbB2 enhances radiation-induced NF-kappaB activation

21 January 2018

1 reference

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Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway

21 January 2018

1 reference

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The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis

21 January 2018

1 reference

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Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector.

21 January 2018

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Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways

21 January 2018

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The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

21 January 2018

1 reference

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Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB

21 January 2018

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Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

21 January 2018

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Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

21 January 2018

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Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB

21 January 2018

1 reference

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Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-κB-dependent process

21 January 2018

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Tumor necrosis factor receptor-associated factor 1 gene overexpression in B-cell chronic lymphocytic leukemia: analysis of NF-kappa B/Rel-regulated inhibitors of apoptosis

21 January 2018

1 reference

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Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61).

21 January 2018

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Death receptors and melanoma resistance to apoptosis

21 January 2018

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Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

21 January 2018

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IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy

21 January 2018

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Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.

21 January 2018

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TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

21 January 2018

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Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

21 January 2018

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Resistance of human ovarian cancer cells to tumor necrosis factor alpha is a consequence of nuclear factor kappaB-mediated induction of Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory protein

21 January 2018

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21 January 2018

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A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis

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NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach

21 January 2018

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

21 January 2018

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

21 January 2018

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Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers?

21 January 2018

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Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP.

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21 January 2018

Identifiers

DOI

10.1074/JBC.M402305200

1 reference

21 September 2017

1 reference