Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts (Q44539657)

4 December 2017

Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts (English)

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4 December 2017

Mikael S Lindström

1

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4 December 2017

Klas G Wiman

series ordinal

2

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4 December 2017

language of work or name

English

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publication date

1 August 2003

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4 December 2017

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4 December 2017

22

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4 December 2017

32

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4 December 2017

4993-5005

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206659

4 December 2017

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cites work

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

21 January 2018

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Caffeine does not cause override of the G2/M block induced by UVc or gamma radiation in normal human skin fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

Immortalisation and transformation revisited

21 January 2018

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Transient excess of MYC activity can elicit genomic instability and tumorigenesis

21 January 2018

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Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts

21 January 2018

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Identification of CDK4 as a target of c-MYC.

21 January 2018

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Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

Does the ribosome translate cancer?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

The INK4A/ARF locus and its two gene products

21 January 2018

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21 January 2018

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Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures

21 January 2018

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p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

p53-Mdm2--the affair that never ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

ATM is a target for positive regulation by E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Inhibition of v-Abl transformation by p53 and p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Direct activation of RNA polymerase III transcription by c-Myc

1 reference

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7 January 2021

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Inactivation of Myc-induced p53-dependent apoptosis in human tumors.

1 reference

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7 January 2021

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Differential activity of conditional MYC and its variant MYC-S in human mortal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

1 reference

7 January 2021

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206659

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206659

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Dimensions Publication ID

4 December 2017

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