Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems. (Q45876651)

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21 January 2020

title

Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems (English)

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2

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Arijit Biswas

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Suzanne M Buckley

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author name string

C N Mattar

1

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N Johana

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X W Ng

5

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A S Fisk

6

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L G Tan

8

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A A Rahim

9

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M H Tan

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J Lu

12

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M Choolani

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J K Y Chan

14

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N M Fisk

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language of work or name

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26 January 2012

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21 January 2020

volume

20

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page(s)

69-83

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issue

1

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https://scigraph.springernature.com/pub.10.1038/gt.2011.216

21 January 2020

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0 references

cites work

Gene therapy in the CNS.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

In utero gene transfer to the mouse nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Drug and gene targeting to the brain with molecular Trojan horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Functional effectiveness of the blood-brain barrier to small water-soluble molecules in developing and adult opossum (Monodelphis domestica)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Hematopoietic cell transplantation for inherited metabolic diseases: an overview of outcomes and practice guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Correction of mucopolysaccharidosis type IIIA somatic and central nervous system pathology by lentiviral-mediated gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Adeno-associated virus serotypes: vector toolkit for human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Clades of Adeno-associated viruses are widely disseminated in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Failure of SCID-X1 gene therapy in older patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Tight junctions of the blood-brain barrier: development, composition and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Gene therapy progress and prospects: fetal gene therapy--first proofs of concept--some adverse effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

In utero gene therapy: current challenges and perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Genetic correction of the fetal brain increases the lifespan of mice with the severe multisystemic disease mucopolysaccharidosis type VII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Of mice and not men: differences between mouse and human immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV9 trans-blood-brain barrier gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Ontogeny of cellular immunity in the human fetus: development of responses to phytohemagglutinin and to allogeneic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

The nonhuman primate as a model of developmental immunotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Cellular and genetic mechanisms of self tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Stable human FIX expression after 0.9G intrauterine gene transfer of self-complementary adeno-associated viral vector 5 and 8 in macaques

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Prions hijack tunnelling nanotubes for intercellular spread

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Prion-like transmission of protein aggregates in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

AAV2/8-mediated correction of OTC deficiency is robust in adult but not neonatal Spf(ash) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

A cell-penetrating peptide suppresses inflammation by inhibiting NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

A limited number of transducible hepatocytes restricts a wide-range linear vector dose response in recombinant adeno-associated virus-mediated liver transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

AAV-mediated gene therapy for metabolic diseases: dosage and reapplication studies in the molybdenum cofactor deficiency model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Successful expression of beta-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Persistent expression of hF.IX After tolerance induction by in utero or neonatal administration of AAV-1-F.IX in hemophilia B mice

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

The eye and inherited metabolic disease: a review.

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Pleiotropic genetic syndromes with developmental abnormalities associated with obesity

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Abetalipoproteinemia: two case reports and literature review

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

Improved metabolic correction in patients with lysosomal storage disease treated with hematopoietic stem cell transplant compared with enzyme replacement therapy

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1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.216

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Induction of stable prenatal tolerance to beta-galactosidase by in utero gene transfer into preimmune sheep fetuses

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1 reference

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