Biochemical and biological characterization of tumor-associated mutations of p110alpha. (Q45961245)

18 December 2017

title

Biochemical and biological characterization of tumor-associated mutations of p110alpha. (English)

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18 December 2017

author

Jonathan Ross Hart

3

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18 December 2017

Peter K. Vogt

6

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18 December 2017

Li Zhao

5

object named as

Li Zhao

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18 December 2017

author name string

Adam Denley

1

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18 December 2017

Marco Gymnopoulos

2

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18 December 2017

Hao Jiang

4

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18 December 2017

language of work or name

English

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publication date

1 January 2008

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18 December 2017

published in

Methods in Enzymology

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18 December 2017

volume

438

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18 December 2017

page(s)

291-305

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18 December 2017

Role of translocation in the activation and function of protein kinase B

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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

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BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.

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7 January 2021

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7 January 2021

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

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High-throughput oncogene mutation profiling in human cancer

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Failure to farnesylate Rheb protein contributes to the enrichment of G0/G1 phase cells in the Schizosaccharomyces pombe farnesyltransferase mutant

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Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

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The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells

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The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

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Identifiers

DOI

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18 December 2017

PubMed ID

18413256

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18 December 2017