Systemic gene delivery to the central nervous system using Adeno-associated virus (Q33695674)

28 July 2017

Systemic gene delivery to the central nervous system using Adeno-associated virus (English)

1 reference

28 July 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Nathalie Dutheil

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Erwan Bezard

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Benjamin Dehay

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Mathieu Bourdenx

1

1 reference

PubMed ID

24917785

28 July 2017

Nathalie Dutheil

2

1 reference

PubMed ID

24917785

28 July 2017

Erwan Bezard

3

1 reference

PubMed ID

24917785

28 July 2017

Benjamin Dehay

4

1 reference

28 July 2017

2 June 2014

1 reference

Frontiers in Molecular Neuroscience

28 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

7

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7 June 2020

page(s)

50

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

Adeno-associated virus vectors and neurological gene therapy

7 June 2020

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons

21 June 2018

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Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders

21 June 2018

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Adeno-associated virus antibody profiles in newborns, children, and adolescents

21 June 2018

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Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system

21 June 2018

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The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

21 June 2018

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Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates

21 June 2018

1 reference

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Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

21 June 2018

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Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV9 trans-blood-brain barrier gene delivery

21 June 2018

1 reference

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Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer

21 June 2018

1 reference

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Terminal N-linked galactose is the primary receptor for adeno-associated virus 9.

21 June 2018

1 reference

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Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder

21 June 2018

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MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression

21 June 2018

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Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

21 June 2018

1 reference

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Expansive gene transfer in the rat CNS rapidly produces amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed

21 June 2018

1 reference

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Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

21 June 2018

1 reference

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RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

21 June 2018

1 reference

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Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB).

21 June 2018

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

21 June 2018

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Long-term luciferase expression monitored by bioluminescence imaging after adeno-associated virus-mediated fetal gene delivery in rhesus monkeys (Macaca mulatta).

21 June 2018

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Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

21 June 2018

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Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery

21 June 2018

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Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production

21 June 2018

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Mannitol-facilitated CNS entry of rAAV2 vector significantly delayed the neurological disease progression in MPS IIIB mice

21 June 2018

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Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons

21 June 2018

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

21 June 2018

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Tailoring the AAV vector capsid for gene therapy.

21 June 2018

1 reference

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Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

21 June 2018

1 reference

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Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

21 June 2018

1 reference

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In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses

21 June 2018

1 reference

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Tau expression levels from various adeno-associated virus vector serotypes produce graded neurodegenerative disease states

21 June 2018

1 reference

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Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

21 June 2018

1 reference

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 June 2018

1 reference

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The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040820

Adeno-associated virus serotypes: vector toolkit for human gene therapy

21 June 2018

1 reference

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Improved high-capacity adenoviral vectors for high-level neuron-restricted gene transfer to the CNS.

21 June 2018

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors

21 June 2018

1 reference

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A combination of mutations enhances the neurotropism of AAV-2.

21 June 2018

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Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis

21 June 2018

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Clades of Adeno-associated viruses are widely disseminated in human tissues.

21 June 2018

1 reference

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Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

21 June 2018

1 reference

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Drug and gene targeting to the brain with molecular Trojan horses

21 June 2018

1 reference

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Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

21 June 2018

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Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

21 June 2018

1 reference

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Insertional mutagenesis of AAV2 capsid and the production of recombinant virus

21 June 2018

1 reference

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Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

21 June 2018

1 reference

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New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors

21 June 2018

1 reference

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Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

21 June 2018

1 reference

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Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells

21 June 2018

1 reference

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Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells

21 June 2018

1 reference

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Adeno-associated virus general transduction vectors: analysis of proviral structures

21 June 2018

1 reference

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Structure of the mouse tyrosine hydroxylase gene

21 June 2018

1 reference

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Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

21 June 2018

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In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous

21 January 2018

1 reference

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Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2014.00050

Levodopa gains psychostimulant-like properties after nigral dopaminergic loss.

21 January 2018

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Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs.

21 January 2018

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Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

21 January 2018

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Novel tools for production and purification of recombinant adenoassociated virus vectors

21 January 2018

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Systemic delivery of tyrosine-mutant AAV vectors results in robust transduction of neurons in adult mice

21 January 2018

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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

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21 January 2018

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Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems.

21 January 2018

1 reference

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Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

21 January 2018

1 reference

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Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors

21 January 2018

1 reference

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Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2014.00050

The neonatal blood-brain barrier is functionally effective, and immaturity does not explain differential targeting of AAV9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2014.00050

Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain

21 January 2018

1 reference

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A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.3389/FNMOL.2014.00050

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917785%20AND%20SRC:MED&resulttype=core&format=json