SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling (Q36728656)

15 August 2017

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title

SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling (English)

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15 August 2017

Hitoshi Shimano

1

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15 August 2017

6 February 2007

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Journal of Molecular Medicine

15 August 2017

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15 August 2017

85

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15 August 2017

437-444

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15 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s00109-007-0158-5

15 August 2017

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cites work

Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0158-5

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-007-0158-5

Novel concepts in insulin regulation of hepatic gluconeogenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-007-0158-5

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

21 January 2018

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Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

21 January 2018

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12 December 2020

Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.

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12 December 2020

LXRs: new therapeutic targets in atherosclerosis?

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12 December 2020

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

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12 December 2020

Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver

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12 December 2020

Signalling mechanisms linking hepatic glucose and lipid metabolism

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12 December 2020

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

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12 December 2020

A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

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12 December 2020

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells

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12 December 2020

Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs

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12 December 2020

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif

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12 December 2020

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

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12 December 2020

Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

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12 December 2020

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

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12 December 2020

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

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12 December 2020

Fatty acid regulation of hepatic gene transcription.

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12 December 2020

Liver X Receptor Signaling Pathways in Cardiovascular Disease

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Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism

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12 December 2020

Role of AMP-activated protein kinase in mechanism of metformin action

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12 December 2020

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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12 December 2020

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

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12 December 2020

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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12 December 2020

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

1 reference

12 December 2020

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

1 reference

12 December 2020

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

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12 December 2020

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene

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12 December 2020

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

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12 December 2020

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury

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12 December 2020

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

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12 December 2020

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

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12 December 2020

Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor.

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12 December 2020

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

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12 December 2020

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

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12 December 2020

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

1 reference

12 December 2020

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

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12 December 2020

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.

1 reference

12 December 2020

Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake

1 reference

12 December 2020

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

1 reference

12 December 2020

Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene

1 reference

12 December 2020

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

1 reference

12 December 2020

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

1 reference

12 December 2020

10.1007/S00109-007-0158-5

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17279346