Mechanisms of transcription factor deregulation in lymphoid cell transformation (Q36970219)

17 August 2017

1 reference

title

Mechanisms of transcription factor deregulation in lymphoid cell transformation (English)

1 reference

17 August 2017

O'Neil J

1

1 reference

PubMed ID

17934490

17 August 2017

Look AT

series ordinal

2

1 reference

PubMed ID

17934490

17 August 2017

language of work or name

English

0 references

publication date

1 October 2007

1 reference

17 August 2017

1 reference

17 August 2017

26

1 reference

17 August 2017

47

1 reference

17 August 2017

6838-6849

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210766

17 August 2017

0 references

cites work

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Molecular genetics of acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Oncogenic conversion of transcription factors by chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Pax5: the guardian of B cell identity and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Non-transcriptional control of DNA replication by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The 2p breakpoint of a 2;8 translocation in Burkitt lymphoma interrupts the V kappa locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Genomic targets of the human c-Myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Gene expression profiling in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A common mechanism of chromosomal translocation in T- and B-cell neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Origins of chromosome translocations in childhood leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of cytogenetic aberration at 10q24: a study from the Children's Cancer Group (CCG)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Oncogenic transcription factors in the human acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

High incidence of Hox11L2 expression in children with T-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Molecular analysis of the t(1;19) breakpoint cluster region in pre-B cell acute lymphoblastic leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

MLL targets SET domain methyltransferase activity to Hox gene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Activating Notch1 mutations in mouse models of T-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

c-Myb regulates the proliferation of immature thymocytes following beta-selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Chromosomal translocations in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Notch regulation of lymphocyte development and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Characterization and developmental expression of Tlx-1, the murine homolog of HOX11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Tel induces a G1 arrest and suppresses Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

An RNA polymerase II elongation factor encoded by the human ELL gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Rnx deficiency results in congenital central hypoventilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) Burkitt lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Multiple functions of Notch signaling in self-renewing organs and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

The oncoprotein MLL-ENL disturbs hematopoietic lineage determination and transforms a biphenotypic lymphoid/myeloid cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

A variant translocation places the λ immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Hox11 controls the genesis of the spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Turning on a dimer: new insights into MLL chimeras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

A fate worse than death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Rearrangements of genes for the antigen receptor on T cells as markers of lineage and clonality in human lymphoid neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210766

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210766

1 reference

17 August 2017

1 reference

PubMed ID

17934490