Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage. (Q37589643)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24600453%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

review article

1 reference

title

Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage (English)

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9 March 2020

2

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9 March 2020

author name string

Leen Moens

series ordinal

1

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9 March 2020

publication date

18 February 2014

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9 March 2020

published in

Frontiers in Immunology

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9 March 2020

volume

5

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9 March 2020

page(s)

65

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Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

9 March 2020

cites work

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25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Interleukin 13 is a B cell stimulating factor

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Specific collaboration between T and B lymphocytes across a cell impermeable membrane in vitro.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

IL-2 dependence of the promotion of human B cell differentiation by IL-6 (BSF-2).

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Interleukin 8 (IL-8) selectively inhibits immunoglobulin E production induced by IL-4 in human B cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Interleukin-21 is increased in active systemic lupus erythematosus patients and contributes to the generation of plasma B cells.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

IL-21 receptor is critical for the development of memory B cell responses.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Membrane tumour necrosis factor-alpha is involved in the polyclonal B-cell activation induced by HIV-infected human T cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Generation of memory B cells and plasma cells in vitro.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Endogenous interleukin 6 plays an obligatory role in interleukin 4-dependent human IgE synthesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927127

A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

3 December 2018

1 reference

12 December 2020

Impaired antibody responses in the hyperimmunoglobulin E syndrome

1 reference

12 December 2020

Antibody responses to protein, polysaccharide, and ΦX174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome

1 reference

12 December 2020

Interferon-alpha can synergize with interleukin 2 for human in vitro antibody response

1 reference

12 December 2020

Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity

1 reference

12 December 2020

IL-21 induces the apoptosis of resting and activated primary B cells

1 reference

12 December 2020

The role of IL-10 in human B cell activation, proliferation, and differentiation

1 reference

12 December 2020

Effect of recombinant IL 2 and gamma-IFN on proliferation and differentiation of human B cells

1 reference

12 December 2020

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

1 reference

12 December 2020

Local suppression of IL-21 in submandibular glands retards the development of Sjögren's syndrome in non-obese diabetic mice

1 reference

12 December 2020

The roles of T cell factors in activation, cell cycle progression, and differentiation of human B cells

1 reference

12 December 2020

Generation and analysis of interleukin-4 deficient mice

1 reference

12 December 2020

Mouse IL-13 enhances antibody production in vivo and acts directly on B cells in vitro to increase survival and hence antibody production

1 reference

12 December 2020

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy

1 reference

12 December 2020

Cutting edge: IL-21 derived from human follicular helper T cells acts as a survival factor for secondary lymphoid organ, but not for bone marrow, plasma cells

1 reference

12 December 2020

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner

1 reference

12 December 2020

Initiation of antibody production to sheep erythrocytes in vitro: replacement of the requirement for T-cells with a cell-free factor isolated from cultures of lymphoid cells

1 reference

12 December 2020

STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion

1 reference

12 December 2020

Antigen-nonspecific T cell-derived factors in B cell activation: differences in the requirements for interleukin 2 in responses of unprimed and primed B cells

1 reference

12 December 2020

Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production

1 reference

12 December 2020

Immunomodulatory role of IL-4 on the secretion of Ig by human B cells

1 reference

12 December 2020

Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway

1 reference

12 December 2020

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells

1 reference

12 December 2020

Inhibitory influence of IL-4 on human B cell responsiveness

1 reference

12 December 2020

T cell-dependent activation of B cell proliferation and differentiation by immobilized monoclonal antibodies to CD3

1 reference

12 December 2020

Generation of nondividing high rate Ig-secreting plasma cells in cultures of human B cells stimulated with anti-CD3-activated T cells

1 reference

12 December 2020

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation

1 reference

12 December 2020

The interplay of interleukin-10 (IL-10) and interleukin-2 (IL-2) in humoral immune responses: IL-10 synergizes with IL-2 to enhance responses of human B lymphocytes in a mechanism which is different from upregulation of CD25 expression

1 reference

12 December 2020

Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines

1 reference

12 December 2020

Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis

1 reference

12 December 2020

The effects of interleukin-1, interleukin-2, alpha-interferon, and gamma-interferon on human B lymphocytes

1 reference

12 December 2020

The plasma cellular reaction and its relation to the formation of antibodies in vitro

1 reference

12 December 2020

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2014.00065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24600453%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24600453%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24600453%20AND%20SRC:MED&resulttype=core&format=json