Ceramide formation as a target in beta-cell survival and function (Q37884074)

24 August 2017

1 reference

title

Ceramide formation as a target in beta-cell survival and function (English)

1 reference

24 August 2017

1 reference

3

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24 August 2017

Florian Lang

1

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PubMed ID

21635197

24 August 2017

Susanne Ullrich

series ordinal

2

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PubMed ID

21635197

24 August 2017

language of work or name

English

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publication date

2 June 2011

1 reference

Expert Opinion on Therapeutic Targets

24 August 2017

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24 August 2017

15

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24 August 2017

9

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24 August 2017

1061-1071

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Sphingomyelinases in cell regulation

24 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Acid sphingomyelinase deficiency attenuates bleomycin-induced lung inflammation and fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Vascular barrier regulation by PAF, ceramide, caveolae, and NO - an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide in redox signaling and cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Spingolipids in Multiple Sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Beta-glycosphingolipids improve glucose intolerance and hepatic steatosis of the Cohen diabetic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Genetic determinants of circulating sphingolipid concentrations in European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Raft ceramide in molecular medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide-rich platforms in transmembrane signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Physiological and pathophysiological aspects of ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Differential regulation of AKT, MAPK and GSK3β during C2-ceramide-induced neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

FTY720-induced suicidal erythrocyte death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide in suicidal death of erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Triggering of suicidal erythrocyte death by amphotericin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with amyloid peptides Abeta(1-42) or IAPP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Activation of the sphingomyelinase/ceramide signal transduction pathway in insulin-secreting beta-cells: role in cytokine-induced beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Life and death decisions of the pancreatic beta-cell: the role of fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The acid sphingomyelinase inhibitor SR33557 counteracts TNF-alpha-mediated potentiation of IL-1beta-induced NF-kappaB activation in the insulin-producing cell line Rinm5F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: potential mechanisms underlying ceramide-mediated metabolic dysfunction of the beta cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Mechanisms of pancreatic beta-cell apoptosis in diabetes and its therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Beta-cell apoptosis in type 2 diabetes: quantitative and functional consequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramides in insulin resistance and lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Palmitate-induced inhibition of insulin gene expression in rat islet β-cells involves the ceramide transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Blockage of ceramide metabolism exacerbates palmitate inhibition of pro-insulin gene expression in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Pleiotropic effects of fatty acids on pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

New insights into fatty acid modulation of pancreatic beta-cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The role of lipids in the pathogenesis of muscle insulin resistance and beta cell failure in type II diabetes and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Effects of dietary fatty acids on insulin sensitivity and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Evidence against the involvement of oxidative stress in fatty acid inhibition of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Newly approved and promising antidiabetic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ascorbic acid protects SH-SY5Y neuroblastoma cells from apoptosis and death induced by beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Implication of calpain in neuronal apoptosis. A possible regulation of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

FGF-2 overexpression opposes the beta amyloid toxic injuries to the vascular endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Modulation of neutrophil apoptosis by beta-amyloid proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Amyloid oligomers in diabetic and nondiabetic human pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Islet amyloid polypeptide promotes beta-cell proliferation in neonatal rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Fas-associated death receptor signaling evoked by human amylin in islet beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

High extracellular glucose inhibits exocytosis through disruption of syntaxin 1A-containing lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Causes and cures for endoplasmic reticulum stress in lipotoxic β-cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

siRNA-mediated depletion of endogenous protein phosphatase 2Acalpha markedly attenuates ceramide-activated protein phosphatase activity in insulin-secreting INS-832/13 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide-activated protein phosphatase-2A activity in insulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Down-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sphingolipid metabolite ceramide causes metabolic perturbation contributing to HERG K+ channel dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Tumor necrosis factor alpha and ceramide depolarise the resting membrane potential of thyroid FRTL-5 cells via a protein kinase Czeta-dependent regulation of K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide inhibits the inwardly rectifying potassium current in GH(3) lactotrophs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na(+) current and delayed rectifier K(+) current in rat sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ceramide inhibits L-type calcium channel currents in GH3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

C(6)-ceramide inhibited Na(+) currents by intracellular Ca(2+) release in rat myoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The 2P-domain K+ channels: role in apoptosis and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Roles of K+ channels in regulating tumour cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

HERG K channel conductance promotes H2O2-induced apoptosis in HEK293 cells: cellular mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Nitrosative stress and potassium channel-mediated neuronal apoptosis: is zinc the link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Ion channels and membrane rafts in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Electrophysiology of islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Oxidative stress and beta-cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sulfonylurea induced beta-cell apoptosis in cultured human islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Small molecule inhibitors of acid sphingomyelinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

CD95 Signaling via Ceramide-rich Membrane Rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Observation of Topical Catalysis by Sphingomyelinase Coupled To Microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

Sulfonylurea and glinide reduce insulin content, functional expression of KATP channels, and accelerate apoptotic β-cell death in the chronic phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.588209

10.1517/14728222.2011.588209

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21635197