Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes (Q38184888)

30 August 2017

Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes (English)

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30 August 2017

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3 June 2020

Jan A Ehses

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4

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3 June 2020

author name string

Clara Westwell-Roper

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1

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3 June 2020

Meixia Dan

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4 February 2014

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Immunology & Cell Biology

30 August 2017

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3 June 2020

volume

92

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314-323

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issue

4

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The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality.

3 June 2020

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Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes

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Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement

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Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance

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Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

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Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation

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Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat

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Treatment with Anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study

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7 January 2021

Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes

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7 January 2021

The Inflammasome in Atherosclerosis and Type 2 Diabetes

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7 January 2021

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

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7 January 2021

Interleukin-1 induced impairment in pancreatic islet oxidative metabolism of glucose is potentiated by tumor necrosis factor

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7 January 2021

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

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7 January 2021

Interleukin-1β induces the expression of HSP70, heme oxygenase and Mn-SOD in FACS-purified rat islet β-cells, but not in α-cells

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7 January 2021

Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures

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7 January 2021

Identifiers

DOI

10.1038/ICB.2014.4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492799%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference