Baking, ageing, diabetes: a short history of the Maillard reaction (Q38232036)

31 August 2017

Baking, ageing, diabetes: a short history of the Maillard reaction (English)

1 reference

31 August 2017

2

Thomas Henle

1 reference

31 August 2017

Michael Hellwig

1

1 reference

PubMed ID

25044982

31 August 2017

language of work or name

English

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publication date

9 July 2014

1 reference

Angewandte Chemie International Edition

31 August 2017

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volume

53

1 reference

31 August 2017

39

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31 August 2017

10316-10329

1 reference

Dehydrated Foods, Chemistry of Browning Reactions in Model Systems

31 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Die Maillard-Reaktion in Lebensmitteln und im menschlichen Körper – neue Ergebnisse zu Chemie, Biochemie und Medizin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Creating proteins with novel functionality via the Maillard reaction: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The Maillard reaction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The Maillard reaction in the human body. The main discoveries and factors that affect glycation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Enzymatic repair of Amadori products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Historical perspective of the Maillard reaction in food science

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The Strecker Degradation of α-Amino Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Some biochemically relevant properties of N-substituted fructosamines derived from amino-acids and N-arylglucosylamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Maillard degradation pathways of vitamin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Potent odorants of the roasted powder and brew of Arabica coffee

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Discovery and structure determination of a novel Maillard-derived sweetness enhancer by application of the comparative taste dilution analysis (cTDA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Formation of pyridone derivates from maltose and lactose. XII. Investigations on the Maillard-reaction (authors transl)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Metabolic transit of Amadori products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Determination of Nepsilon-(carboxymethyl)lysine in food systems by ultra performance liquid chromatography-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Advanced glycation end products in foods and a practical guide to their reduction in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Nonenzymatic glycosylation and the pathogenesis of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Amides are novel protein modifications formed by physiological sugars

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modulating activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification and quantification of aminophospholipid-linked Maillard compounds in model systems and egg yolk products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Labeling studies on the formation pathway of Nepsilon-carboxymethyllysine in maillard-type reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Physiological relevance of dietary melanoidins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The energetic significance of cooking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The free amino groups of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The estimation of the available lysine in animal-protein foods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Degradation of fructose amino acids to N-(2-furoylmethyl)amino acids. Intermediates in browning reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The reaction between proteins and reducing sugars in the 'dry' state; relative reactivity of the alpha- and epsilon-amino groups of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

An abnormal hemoglobin in red cells of diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Further identification of the nature and linkage of the carbohydrate in hemoglobin A1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Reaction of monosaccharides with proteins: possible evolutionary significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Nonenzymatic browning in vivo: possible process for aging of long-lived proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Hypothesis. Glucose as a mediator of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The effects of the Maillard reaction on the physical properties and cell interactions of collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Understanding RAGE, the receptor for advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Advanced glycation end products: sparking the development of diabetic vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

RAGE: a novel biological and genetic marker for vascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Binding of receptor for advanced glycation end products (RAGE) ligands is not sufficient to induce inflammatory signals: lack of activity of endotoxin-free albumin-derived advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Advanced glycation end products in uremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Review on uremic toxins: classification, concentration, and interindividual variability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

3,4-Dideoxyglucosone-3-ene (3,4-DGE): a cytotoxic glucose degradation product in fluids for peritoneal dialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Current therapeutic interventions in the glycation pathway: evidence from clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification of fructose 3-phosphate in the lens of diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification of fructosamine residues deglycated by fructosamine-3-kinase in human hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

5-Sulfooxymethylfurfural as a possible ultimate mutagenic and carcinogenic metabolite of the Maillard reaction product, 5-hydroxymethylfurfural

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Toxicology and risk assessment of 5-Hydroxymethylfurfural in food

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Analysis of acrylamide, a carcinogen formed in heated foodstuffs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Acrylamide is formed in the Maillard reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Acrylamide from Maillard reaction products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

In-depth mechanistic study on the formation of acrylamide and other vinylogous compounds by the maillard reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Formation of Pent-4-en-1-amine, the counterpart of acrylamide from lysine and its conversion into piperidine in lysine/glucose reaction mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Review of methods for the reduction of dietary content and toxicity of acrylamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Review of epidemiologic studies of dietary acrylamide intake and the risk of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Reaction on the acrylamide and cancer review by Lipworth and colleagues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

The effects of AGEing on diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Advanced glycation end products and mortality in hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Are food advanced glycation end products toxic in biological systems?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Studies on absorption and elimination of dietary maillard reaction products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

An oral load of the early glycation compound lactuloselysine fails to accumulate in the serum of uraemic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Estimation of hydroxymethylfurfural availability in breakfast cereals. Studies in Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Digestibility of extruded proteins and metabolic transit of N ε -carboxymethyllysine in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Molecular structure in soil humic substances: the new view

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Dietary advanced glycation end products--a risk to human health? A call for an interdisciplinary debate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

A review on the beneficial aspects of food processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Coffee, colon function and colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Influence of feeding malt, bread crust, and a pronylated protein on the activity of chemopreventive enzymes and antioxidative defense parameters in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Maillard reaction products modulating the growth of human tumor cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Studies on the inhibition of tumor cell growth and microtubule assembly by 3-hydroxy-4-[(E)-(2-furyl)methylidene]methyl-3-cyclopentene-1,2-dione, an intensively coloured Maillard reaction product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

High molecular weight coffee melanoidins are inhibitors for matrix metalloproteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Microstratigraphic evidence of in situ fire in the Acheulean strata of Wonderwerk Cave, Northern Cape province, South Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Biochemical and Nutritional Significance of the Reaction between Proteins and Reducing Sugars

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

Interaction Between Simple Sugars and Amino-Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201308808

21 January 2018

Identifiers

DOI

10.1002/ANIE.201308808

1 reference

31 August 2017

1 reference

PubMed ID

25044982