Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases (Q38236295)

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scientific article published on 03 August 2014

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English	Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases	scientific article published on 03 August 2014

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scholarly article

1 reference

Europe PubMed Central

31 August 2017

6 references

17 June 2019

7 November 2019

19 November 2019

28 August 2020

21 June 2021

8 October 2022

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases (English)

1 reference

Europe PubMed Central

31 August 2017

cardiovascular disease

4 references

17 June 2019

7 November 2019

19 November 2019

28 August 2020

metabolic disease

6 references

17 June 2019

7 November 2019

19 November 2019

28 August 2020

21 June 2021

8 October 2022

1 reference

7 November 2019

1 reference

7 November 2019

1 reference

19 November 2019

1 reference

based on heuristic

inferred from title

circulatory system

1 reference

based on heuristic

inferred from title

cyclopentane monoterpenoid

1 reference

28 August 2020

phenylethyl alcohol

1 reference

21 June 2021

Tiziana Montalcini

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086598%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Stefania Bulotta

1

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1 June 2020

Marilena Celano

2

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1 June 2020

Saverio Massimo Lepore

3

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Arturo Pujia

5

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Diego Russo

6

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1 June 2020

language of work or name

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publication date

3 August 2014

7 references

Europe PubMed Central

31 August 2017

17 June 2019

7 November 2019

19 November 2019

28 August 2020

21 June 2021

8 October 2022

Journal of Translational Medicine

7 references

17 June 2019

7 November 2019

19 November 2019

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086598%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

28 August 2020

21 June 2021

8 October 2022

12

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219

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1 June 2020

copyright license

Creative Commons Attribution 4.0 International

6 references

Europe PubMed Central

17 June 2019

Europe PubMed Central

7 November 2019

Europe PubMed Central

19 November 2019

Europe PubMed Central

28 August 2020

Europe PubMed Central

21 June 2021

Europe PubMed Central

8 October 2022

copyright status

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on focus list of Wikimedia project

0 references

https://scigraph.springernature.com/pub.10.1186/s12967-014-0219-9

0 references

Hydroxytyrosol and its potential therapeutic effects

1 reference

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Antioxidant and antigrowth action of peracetylated oleuropein in thyroid cancer cells

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Hydroxytyrosol promotes superoxide production and defects in autophagy leading to anti-proliferation and apoptosis on human prostate cancer cells.

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Mediterranean diet and health

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Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial

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Health effects of olive oil polyphenols: recent advances and possibilities for the use of health claims

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Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol

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Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: a review of in vitro studies

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Hydroxytyrosol protects against oxidative DNA damage in human breast cells

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Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil.

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Biological activities of phenolic compounds present in virgin olive oil.

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Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity

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Olive tree (Olea europaea) leaves: potential beneficial effects on human health.

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Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells.

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6 September 2017

The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health

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6 September 2017

Akt/FOXO3a/SIRT1-mediated cardioprotection by n-tyrosol against ischemic stress in rat in vivo model of myocardial infarction: switching gears toward survival and longevity

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Olive oil, the mediterranean diet, and cardiovascular health

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6 September 2017

Oxidative DNA damage is prevented by extracts of olive oil, hydroxytyrosol, and other olive phenolic compounds in human blood mononuclear cells and HL60 cells

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6 September 2017

Phenolic molecules in virgin olive oils: a survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade.

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Vasculoprotective potential of olive oil components.

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6 September 2017

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells.

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6 September 2017

Oxidative stress and cancer: have we moved forward?

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6 September 2017

The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits.

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6 September 2017

Safety assessment of aqueous olive pulp extract as an antioxidant or antimicrobial agent in foods

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6 September 2017

Evaluation of the antioxidant capacity of individual phenolic compounds in virgin olive oil.

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Health and sensory properties of virgin olive oil hydrophilic phenols: agronomic and technological aspects of production that affect their occurrence in the oil.

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Antioxidant and other biological activities of phenols from olives and olive oil.

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6 September 2017

Mediterranean diet pyramid: a cultural model for healthy eating

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31 August 2018

Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil

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Anti-proliferative and pro-apoptotic activities of hydroxytyrosol on different tumour cells: the role of extracellular production of hydrogen peroxide.

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6 September 2017

Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-β-induced toxicity. Involvement of the NF-κB signaling

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Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells

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Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

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Antiviral efficacy against hepatitis B virus replication of oleuropein isolated from Jasminum officinale L. var. grandiflorum

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Antimicrobial properties of oleuropein and products of its hydrolysis from green olives.

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Evaluation of effect of oleuropein on skin wound healing in aged male BALB/c mice

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Cardioprotective and neuroprotective roles of oleuropein in olive.

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Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein

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23 June 2018

Oleuropein as a bioactive constituent added in milk and yogurt.

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31 August 2018

Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer.

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31 August 2018

Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism.

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31 August 2018

Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells.

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31 August 2018

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

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31 August 2018

Role of the inhibition of oxidative stress and inflammatory mediators in the neuroprotective effects of hydroxytyrosol in rat brain slices subjected to hypoxia reoxygenation.

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31 August 2018

Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury

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31 August 2018

The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice.

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31 August 2018

Direct enrichment of olive oil in oleuropein by ultrasound-assisted maceration at laboratory and pilot plant scale.

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31 August 2018

Oleuropein and derivatives from olives as Tau aggregation inhibitors.

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31 August 2018

Olive oil polyphenol oleuropein inhibits smooth muscle cell proliferation.

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31 August 2018

Study of the interaction between the amyloid beta peptide (1-40) and antioxidant compounds by nuclear magnetic resonance spectroscopy.

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31 August 2018

Hepatoprotective effect of oleuropein in mice: mechanisms uncovered by gene expression profiling.

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31 August 2018

Effects of olive leaf extract and its main component oleuroepin on acute ultraviolet B irradiation-induced skin changes in C57BL/6J mice

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31 August 2018

Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats

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31 August 2018

Production of hydrogen peroxide is responsible for the induction of apoptosis by hydroxytyrosol on HL60 cells.

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31 August 2018

Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats.

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31 August 2018

Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol

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31 August 2018

Influence of the decrease in oxygen during malaxation of olive paste on the composition of volatiles and phenolic compounds in virgin olive oil.

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31 August 2018

Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves

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31 August 2018

Effects of hydroxytyrosol and hydroxytyrosol acetate administration to rats on platelet function compared to acetylsalicylic acid.

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31 August 2018

Lipid-lowering and antioxidant effects of hydroxytyrosol and its triacetylated derivative recovered from olive tree leaves in cholesterol-fed rats

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31 August 2018

Inhibition of cell cycle progression by hydroxytyrosol is associated with upregulation of cyclin-dependent protein kinase inhibitors p21(WAF1/Cip1) and p27(Kip1) and with induction of differentiation in HL60 cells.

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31 August 2018

Flaxseed oil supplementation does not affect plasma lipoprotein concentration or particle size in human subjects

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31 August 2018

Noncovalent interaction between amyloid-beta-peptide (1-40) and oleuropein studied by electrospray ionization mass spectrometry

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31 August 2018

Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits

1 reference

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31 August 2018

Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor

1 reference

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31 August 2018

Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion

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31 August 2018

Sunflower oil does not protect against LDL oxidation as virgin olive oil does in patients with peripheral vascular disease.

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31 August 2018

Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals

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31 August 2018

Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation

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31 August 2018

Comparison of the antioxidant activities of extra virgin olive oils.

1 reference

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31 August 2018

Acid hydrolysis of secoiridoid aglycons during storage of virgin olive oil.

1 reference

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31 August 2018

Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237885

31 August 2018

On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237885

31 August 2018

The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237885

3 December 2018

Lipophilic Hydroxytyrosol Esters: Fatty Acid Conjugates for Potential Topical Administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free Radical-Scavenging Properties of Olive Oil Polyphenols

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oleuropein prevents ethanol-induced gastric ulcers via elevation of antioxidant enzyme activities in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of olive stoning on the volatile and phenolic composition of virgin olive oil

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of olive leaf

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative antibacterial and antifungal effects of some phenolic compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the influence of thermal oxidation on the phenolic composition and on the antioxidant activity of extra-virgin olive oils

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irrigation effects on quality, phenolic composition, and selected volatiles of virgin olive oils cv. Leccino

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of minor constituents of olive oil on cardiovascular disease: new findings

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effect of oleuropein following spinal cord injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25086598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12967-014-0219-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086598%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086598%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25086598%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

ResearchGate publication ID

0 references

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