Inflammasome activation and function in liver disease (Q38521274)

3 September 2017

1 reference

title

Inflammasome activation and function in liver disease (English)

1 reference

3 September 2017

1 reference

Gyongyi Szabo

1

1 reference

3 September 2017

Jan Petrasek

series ordinal

2

1 reference

3 September 2017

language of work or name

English

0 references

publication date

9 June 2015

1 reference

Nature Reviews Gastroenterology & Hepatology

3 September 2017

published in

1 reference

3 September 2017

volume

12

1 reference

3 September 2017

issue

7

1 reference

3 September 2017

page(s)

387-400

1 reference

Approaching the asymptote? Evolution and revolution in immunology

3 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caught red-handed: uric acid is an agent of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Toll-like receptors and adaptor molecules in liver disease: update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Microbiota-liver axis in hepatic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Toll-like receptor signaling in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Innate immunity in alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Pattern recognition receptors: a contemporary view on liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Sterile inflammation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Sterile inflammation: sensing and reacting to damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome: first line of the immune response to cell stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammasomes in liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Pathogen recognition by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Uric acid as a danger signal in gout and its comorbidities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Hexokinase II binding to mitochondria is necessary for Kupffer cell activation and is potentiated by ethanol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Type I Interferons Protect From Toll-Like Receptor 9–Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cell Death and Fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome: an integrated view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome NLRs in immunity, inflammation, and associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin 33: a switch-hitting cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

IL-33 is a crucial amplifier of innate rather than acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasomes: mechanisms of activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

A functional role for Nlrp6 in intestinal inflammation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

21 January 2018

Alcoholic liver disease.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Signalling pathways in alcohol-induced liver inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Serum interleukin-1 (IL-1) activity in alcoholic hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Alcoholic liver disease: pathogenesis and new therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Lycium barbarum polysaccharide attenuates alcoholic cellular injury through TXNIP-NLRP3 inflammasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Gut-liver axis in alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Alcohol and mitochondria: a dysfunctional relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interrelation of uric acid and ethanol metabolism in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Metabolic syndrome, alcohol consumption and genetic factors are associated with serum uric acid concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

High mobility group box-1 (HMGB1) participates in the pathogenesis of alcoholic liver disease (ALD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Immune and inflammatory pathways in NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome in liver injury and non-alcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The inflammasome: a remote control for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

High fat diet feeding results in gender specific steatohepatitis and inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP3 inflammasome activation is required for fibrosis development in NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The Gordian Knot of dysbiosis, obesity and NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Gender and racial differences in nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Differences in innate immune signaling between alcoholic and non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Global distribution and prevalence of hepatitis C virus genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Innate immune cell networking in hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

21 January 2018

Innate immunity and HCV.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Viral and Host Factors Induce Macrophage Activation and Loss of Toll-Like Receptor Tolerance in Chronic HCV Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

No evidence for caspase-dependent apoptosis in acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Uric acid promotes an acute inflammatory response to sterile cell death in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Liver ischemia/reperfusion injury: Processes in inflammatory networks-A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Ischemia/Reperfusion injury in liver surgery and transplantation: pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Ischaemia-reperfusion injury in liver transplantation--from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Hepatic microcirculation in fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

BH3-only proteins contribute to steatotic liver ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Transfer of the interleukin-1 receptor antagonist gene into rat liver abrogates hepatic ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin 18 causes hepatic ischemia/reperfusion injury by suppressing anti-inflammatory cytokine expression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammasome-mediated regulation of hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammasome biology in fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

TLR4 enhances TGF-beta signaling and hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Effect of interferon-alpha, ribavirin, pentoxifylline, and interleukin-18 antibody on hepatitis C sera-stimulated hepatic stellate cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin-1 participates in the progression from liver injury to fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Differential effects of alcohol drinking pattern on liver enzymes in men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Drinking patterns, dependency and life-time drinking history in alcohol-related liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Steatohepatitis: a tale of two "hits"?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

First-in-class pan caspase inhibitor developed for the treatment of liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Blockade of interleukin 1 in type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Safety and tolerability of canakinumab, an IL-1β inhibitor, in type 2 diabetes mellitus patients: a pooled analysis of three randomised double-blind studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caspase inhibitors: viral, cellular and chemical

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Escherichia coli antibodies in alcoholic liver disease. Correlation to alcohol consumption, alcoholic hepatitis, and serum IgA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Toll-like receptors in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Antibiotics regulate the immune response in both presence and absence of lipopolysaccharide through modulation of Toll-like receptors, cytokine production and phagocytosis in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Argininosuccinate synthetase as a plasma biomarker of liver injury after acetaminophen overdose in rodents and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Elovl6 promotes nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Tolerance, danger, and the extended family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Protective role of IL-33/ST2 axis in Con A-induced hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Pretreatment with soluble ST2 reduces warm hepatic ischemia/reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Recombinant ST2 boosts hepatic Th2 response in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Inflammasome and toll-like receptor 9: Partners in crime in toxic liver injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Gene silencing of NALP3 protects against liver ischemia-reperfusion injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Alcohol drinking pattern and risk of alcoholic liver cirrhosis: A prospective cohort study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Clinical Trial of the Pan-Caspase Inhibitor, IDN-6556, in Human Liver Preservation Injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.94

Interleukin-18, a proinflammatory cytokine.

31 March 2020

1 reference

12 December 2020

Canakinumab, a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders.

1 reference

12 December 2020

Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice

1 reference

12 December 2020

Steatotic livers. Can we use them in OLTX? Outcome data from a prospective baseline liver biopsy study

1 reference

12 December 2020

Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes

1 reference

12 December 2020

Liver disease in women. Alcohol, autoimmunity, and gallstones

1 reference

12 December 2020

Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology

1 reference

12 December 2020

Use of cultured cells to study alcohol metabolism

1 reference

12 December 2020

Allopurinol prevents early alcohol-induced liver injury in rats

1 reference

12 December 2020

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

1 reference

12 December 2020

Response to local inflammation of IL-1 beta-converting enzyme- deficient mice

1 reference

12 December 2020

Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C.

1 reference

12 December 2020

Mechanisms of alcoholic liver disease: cytokines

1 reference

12 December 2020

Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes

1 reference

12 December 2020

Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes

1 reference

12 December 2020

The potential for caspases in drug discovery

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRGASTRO.2015.94

1 reference

Dimensions Publication ID

3 September 2017

1047574127

0 references

1 reference