Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics (Q38857804)

7 September 2017

1 reference

title

Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics (English)

1 reference

7 September 2017

main subject

hepatocellular carcinoma

1 reference

Faisal Saeed Khan

1

1 reference

7 September 2017

Ijaz Ali

2

1 reference

7 September 2017

Ume Kalsoom Afridi

3

1 reference

7 September 2017

Muhammad Ishtiaq

4

1 reference

7 September 2017

Rashid Mehmood

5

1 reference

7 September 2017

publication date

7 June 2016

1 reference

7 September 2017

published in

Hepatology international

1 reference

7 September 2017

volume

11

1 reference

7 September 2017

issue

1

1 reference

7 September 2017

page(s)

45-53

1 reference

Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival

7 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

21 January 2018

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hepatocellular carcinoma: the need for progress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The etiology of hepatocellular carcinoma and consequences for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Viral hepatitis and liver cancer: the case of hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Chronic liver diseases as liver tumor precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

A fresh look at NASH pathogenesis. Part 1: the metabolic movers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Global challenges in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Molecular pathogenesis of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hepatocarcinogenesis in hepatitis viral infection: lessons from transgenic mouse studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Molecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Molecular epidemiology of human liver cancer: insights into etiology, pathogenesis and prevention from The Gambia, West Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hepatocellular carcinoma pathogenesis: from genes to environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

From the metabolic syndrome to NAFLD or vice versa?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Molecular mechanisms involved in NAFLD progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic reprogramming in Mist1(-/-) mice predicts the molecular response to cerulein-induced pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The complex language of chromatin regulation during transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Dnmt3L and the establishment of maternal genomic imprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

CpG islands--'a rough guide'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Evidence for an instructive mechanism of de novo methylation in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic gene silencing in cancer initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

DNA methylation patterns and epigenetic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genomic mapping of 5-hydroxymethylcytosine in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Distribution of 5-hydroxymethylcytosine in different human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone variant H2A.Z is required for early mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone H2A variants in nucleosomes and chromatin: more or less stable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone variants: key players of chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genomic characterization reveals a simple histone H4 acetylation code.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Methylation of histone H3 Lys 4 in coding regions of active genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Active genes are tri-methylated at K4 of histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

A chromatin landmark and transcription initiation at most promoters in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Role of histone H2A ubiquitination in Polycomb silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone demethylation by a family of JmjC domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

microRNAs: tiny regulators with great potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Regulation of microRNA processing in development, differentiation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Smoking induces differential miRNA expression in human spermatozoa: a potential transgenerational epigenetic concern?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Stem cells and cancer; the polycomb connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Altered expression of histone deacetylases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Polycomb group proteins: navigators of lineage pathways led astray in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Role of epigenetics in cancer initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Expression of DNA (5-cytosin)-methyltransferases (DNMTs) in hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Control of microtubule stability by the RASSF1A tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Clinicopathological significance of RASSF1A reduced expression and hypermethylation in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Quantitative analysis of RASSF1A promoter methylation in hepatocellular carcinoma and its prognostic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

High frequency of promoter hypermethylation of RASSF1A in tumor and plasma of patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Combination of serum RASSF1A methylation and AFP is a promising non-invasive biomarker for HCC patient with chronic HBV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Tumor suppression by Ink4a-Arf: progress and puzzles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Role of the p16 tumor suppressor gene in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16INK4A RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hypermethylation of the RUNX3 gene in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

SOCS regulation of the JAK/STAT signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Genetic and epigenetic changes in rat preneoplastic liver tissue induced by 2-acetylaminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

MicroRNA-451: epithelial-mesenchymal transition inhibitor and prognostic biomarker of hepatocelluar carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

RETRACTED: Downregulation of miR-148b as biomarker for early detection of hepatocellular carcinoma and may serve as a prognostic marker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

miR-217 inhibits invasion of hepatocellular carcinoma cells through direct suppression of E2F3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Development and classes of epigenetic drugs for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic drugs against cancer: an evolving landscape

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Trials with 'epigenetic' drugs: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

EZH2 is essential for glioblastoma cancer stem cell maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeuti

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

Epidemiology of Hepatocellular Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12072-016-9743-4

DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1

21 January 2018

1 reference

12 December 2020

DNA methylation markers and serum α-fetoprotein level are prognostic factors in hepatocellular carcinoma.

1 reference

12 December 2020

Quantitative analysis of circulating methylated DNA as a biomarker for hepatocellular carcinoma

1 reference

12 December 2020

High frequency of p16INK4A gene alterations in hepatocellular carcinoma

1 reference

12 December 2020

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells

1 reference

12 December 2020

Molecular pathogenesis of human hepatocellular carcinoma

1 reference

12 December 2020

p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma

1 reference

12 December 2020

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

1 reference

12 December 2020

Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma

1 reference

12 December 2020

Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma

1 reference

12 December 2020

MiR-26b inhibits hepatocellular carcinoma cell proliferation, migration, and invasion by targeting EphA2.

1 reference

12 December 2020

p16 is a major inactivation target in hepatocellular carcinoma

1 reference

12 December 2020

RETRACTED ARTICLE: Profiles of tissue microRNAs; miR-148b and miR-25 serve as potential prognostic biomarkers for hepatocellular carcinoma

1 reference

12 December 2020

Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas.

1 reference

12 December 2020

Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis.

1 reference

12 December 2020

Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP

1 reference

12 December 2020

Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis

1 reference

12 December 2020

Cytosine methylation: the pros and cons of DNA methylation

1 reference

12 December 2020

RNAi screening with shRNAs against histone methylation-related genes reveals determinants of sorafenib sensitivity in hepatocellular carcinoma cells

1 reference

12 December 2020

Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients

1 reference

12 December 2020

miR-503 suppresses metastasis of hepatocellular carcinoma cell by targeting PRMT1

1 reference

12 December 2020

Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma

1 reference

12 December 2020

Rapid activation of the Stat3 transcription complex in liver regeneration

1 reference

12 December 2020

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases

1 reference

12 December 2020

10.1007/S12072-016-9743-4

Identifiers

DOI

1 reference

Dimensions Publication ID

7 September 2017

1014713760

0 references

1 reference