Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies. (Q38862338)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

review article

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title

Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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2

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13 March 2020

author name string

Xueling Wu

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

publication date

10 June 2016

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Current Opinion in Immunology

13 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

42

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13 March 2020

page(s)

56-64

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Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

13 March 2020

cites work

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Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.

17 June 2018

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Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

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The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel

17 June 2018

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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

17 June 2018

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Antibody responses to envelope glycoproteins in HIV-1 infection

17 June 2018

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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

17 June 2018

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

17 June 2018

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

17 June 2018

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

17 June 2018

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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

17 June 2018

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Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

17 June 2018

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Transplanting supersites of HIV-1 vulnerability

17 June 2018

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Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1.

17 June 2018

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Early development of broadly neutralizing antibodies in HIV-1-infected infants

17 June 2018

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17 June 2018

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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

17 June 2018

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.

17 June 2018

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

17 June 2018

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

17 June 2018

1 reference

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Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

17 June 2018

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

17 June 2018

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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

17 June 2018

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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

17 June 2018

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17 June 2018

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

17 June 2018

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17 June 2018

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Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

17 June 2018

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17 June 2018

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17 June 2018

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Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

17 June 2018

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Immune-correlates analysis of an HIV-1 vaccine efficacy trial

17 June 2018

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Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens

17 June 2018

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Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

17 June 2018

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

17 June 2018

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H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

17 June 2018

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Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

17 June 2018

1 reference

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

17 June 2018

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Broad neutralization coverage of HIV by multiple highly potent antibodies

17 June 2018

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

17 June 2018

1 reference

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

17 June 2018

1 reference

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

17 June 2018

1 reference

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

17 June 2018

1 reference

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

17 June 2018

1 reference

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Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

17 June 2018

1 reference

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

17 June 2018

1 reference

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Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand

17 June 2018

1 reference

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Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens

17 June 2018

1 reference

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

17 June 2018

1 reference

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The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design

17 June 2018

1 reference

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

17 June 2018

1 reference

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Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

17 June 2018

1 reference

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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

17 June 2018

1 reference

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

17 June 2018

1 reference

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Predominant autoantibody production by early human B cell precursors

17 June 2018

1 reference

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

17 June 2018

1 reference

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A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

17 June 2018

1 reference

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

17 June 2018

1 reference

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Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development

17 June 2018

1 reference

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

17 June 2018

1 reference

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A role for carbohydrates in immune evasion in AIDS.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

T cell-independent antigens type 2.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

Levels of somatic hypermutations in B cell receptors increase during childhood.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

Limits for antibody affinity maturation and repertoire diversification in hypervaccinated humans

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

Progress in HIV-1 vaccine development

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270

10.1016/J.COI.2016.05.013

22 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

27289425

1 reference