Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation (Q40415917)

20 September 2017

Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation (English)

1 reference

20 September 2017

0 references

Bo-Geon Yun

1

1 reference

PubMed ID

15922741

20 September 2017

Robert L Matts

series ordinal

2

1 reference

PubMed ID

15922741

20 September 2017

language of work or name

English

0 references

publication date

1 April 2005

1 reference

Experimental Cell Research

20 September 2017

1 reference

20 September 2017

307

1 reference

20 September 2017

1

1 reference

20 September 2017

212-223

1 reference

Molecular mechanisms regulating myogenic determination and differentiation

20 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Crosstalk between cell cycle regulators and the myogenic factor MyoD in skeletal myoblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Signaling chromatin to make muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Cell cycle exit upon myogenic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Effect of muscle origin and phenotype on satellite cell muscle-specific gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Structure, regulation and function of PKB/AKT--a major therapeutic target

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Signaling pathways weigh in on decisions to make or break skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Molecular mechanisms modulating muscle mass

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Regulation of cell size and contractile function by AKT in cardiomyocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

ErbB2 pathways in heart and neural diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Essential roles of Her2/erbB2 in cardiac development and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

ErbB2 is required for muscle spindle and myoblast cell survival.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Calcineurin-mediated pathway involved in the differentiated phenotype of smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Akt phosphorylation is not sufficient for insulin-like growth factor-stimulated myogenin expression but must be accompanied by down-regulation of mitogen-activated protein kinase/extracellular signal-regulated kinase phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Activation of Akt2 Inhibits anoikis and apoptosis induced by myogenic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Altered physiology and action of insulin-like growth factor 1 in skeletal muscle in chronic renal failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Gene therapy for cardiac cachexia?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Changes in muscle mass and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The alpha7beta1 integrin in muscle development and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Skeletal muscle LIM protein 1 regulates integrin-mediated myoblast adhesion, spreading, and migration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The collagen receptor integrins have distinct ligand recognition and signaling functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Modulation of cell proliferation and differentiation through substrate-dependent changes in fibronectin conformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Integrin signaling's potential for mediating gene expression in hypertrophying skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

A functional role for specific spliced variants of the alpha7beta1 integrin in acetylcholine receptor clustering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The extracellular matrix protein betaIG-H3 is expressed at myotendinous junctions and supports muscle cell adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

The roles of integrin-linked kinase in the regulation of myogenic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Control of myogenic differentiation by cellular oncogenes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Src-class kinases act within the agrin/MuSK pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Role for cellular Src kinase in myoblast proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Functional interaction of Src family kinases with the acetylcholine receptor in C2 myotubes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Stem cell antigen-1 is necessary for cell-cycle withdrawal and myoblast differentiation in C2C12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Merosin-integrin promotion of skeletal myofiber cell survival: Differentiation state-distinct involvement of p60Fyn tyrosine kinase and p38alpha stress-activated MAP kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Regulation of MyoD function in the dividing myoblast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Structure and functional relationships of Hsp90.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Heat-shock protein 90, a chaperone for folding and regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp90 inhibitors as novel cancer chemotherapeutic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Development of small molecule Hsp90 inhibitors: utilizing both forward and reverse chemical genomics for drug identification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Overview: Translating Hsp90 Biology into Hsp90 Drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Altered states: selectively drugging the Hsp90 cancer chaperone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp90 activation and cell cycle regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Myoblast seeding in a collagen matrix evaluated in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Comparison of initial stages of muscle differentiation in rat and mouse myoblastic and mouse mesodermal stem cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Voltage-activated calcium signals in myotubes loaded with high concentrations of EGTA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Benzoquinoid ansamycins (herbimycin A and geldanamycin) interfere with the maturation of growth factor receptor tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Modulation of Akt kinase activity by binding to Hsp90

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp90-mediated folding of the lymphoid cell kinase p56lck

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Molecular determinants of the physiological adaptation to stress in the cardiomyocyte: a focus on AKT.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Kinases as therapeutic targets for heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Myogenic programs of mouse muscle cell lines: expression of myosin heavy chain isoforms, MyoD1, and myogenin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Functional interaction of human Cdc37 with the androgen receptor but not with the glucocorticoid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Cdc37 goes beyond Hsp90 and kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Activation of MyoD-dependent transcription by cdk9/cyclin T2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Mutation of MyoD-Ser237 abolishes its up-regulation by c-Mos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Casein kinase II increases the transcriptional activities of MRF4 and MyoD independently of their direct phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

A positive feedback loop between protein kinase CKII and Cdc37 promotes the activity of multiple protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.03.003

10.1016/J.YEXCR.2005.03.003

7 January 2021

Identifiers

DOI

1 reference

20 September 2017

1 reference

PubMed ID

15922741