STAT4 and T-bet control follicular helper T cell development in viral infections. (Q47355847)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29212666%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

STAT4 and T-bet control follicular helper T cell development in viral infections (English)

1 reference

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5 April 2020

5

1 reference

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5 April 2020

Jessica K Wang

4

1 reference

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5 April 2020

Susan Kaech

8

1 reference

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5 April 2020

Joseph E. Craft

10

1 reference

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5 April 2020

author name string

Jason S Weinstein

1

1 reference

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5 April 2020

Brian J Laidlaw

2

1 reference

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5 April 2020

Yisi Lu

3

1 reference

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5 April 2020

Ningcheng Li

6

1 reference

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5 April 2020

Edward I Herman

7

1 reference

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5 April 2020

Patrick G Gallagher

9

1 reference

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5 April 2020

language of work or name

English

0 references

publication date

6 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29212666%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

5 April 2020

published in

1 reference

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5 April 2020

volume

215

1 reference

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5 April 2020

issue

1

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5 April 2020

page(s)

337-355

1 reference

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describes a project that uses

5 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5748849/fullTextXML

inferred from PubMed Central ID database lookup

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

15 July 2018

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IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

15 July 2018

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IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

15 July 2018

1 reference

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T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

15 July 2018

1 reference

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Bcl6 mediates the development of T follicular helper cells

15 July 2018

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

15 July 2018

1 reference

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Cytokine-secreting follicular T cells shape the antibody repertoire

15 July 2018

1 reference

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

15 July 2018

1 reference

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Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

15 July 2018

1 reference

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Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

15 July 2018

1 reference

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Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation

15 July 2018

1 reference

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

15 July 2018

1 reference

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Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

15 July 2018

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Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner

15 July 2018

1 reference

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T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

15 July 2018

1 reference

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STAT4 expression in human T cells is regulated by DNA methylation but not by promoter polymorphism.

15 July 2018

1 reference

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T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

15 July 2018

1 reference

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Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

15 July 2018

1 reference

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Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire.

15 July 2018

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B7h is required for T cell activation, differentiation, and effector function

15 July 2018

1 reference

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T-bet regulates T-independent IgG2a class switching

15 July 2018

1 reference

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STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation

15 July 2018

1 reference

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T-bet regulates IgG class switching and pathogenic autoantibody production

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

ICOS is critical for CD40-mediated antibody class switching

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

ICOS co-stimulatory receptor is essential for T-cell activation and function

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

A novel transcription factor, T-bet, directs Th1 lineage commitment

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

FcR gamma chain deletion results in pleiotrophic effector cell defects

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Neutralizing F(ab')2 fragments of protective monoclonal antibodies to yellow fever virus (YF) envelope protein fail to protect mice against lethal YF encephalitis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Germinal-center development of memory B cells driven by IL-9 from follicular helper T cells.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Spontaneous formation of germinal centers in autoimmune mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748849

T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20170457

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

21 January 2018

1 reference

12 December 2020

IL-21 induces the apoptosis of resting and activated primary B cells

1 reference

12 December 2020

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses

1 reference

12 December 2020

Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells

1 reference

12 December 2020

Excessive production of IFN-gamma in patients with systemic lupus erythematosus and its contribution to induction of B lymphocyte stimulator/B cell-activating factor/TNF ligand superfamily-13B

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20170457

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29212666%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29212666%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

PubMed publication ID

29212666

1 reference