Caenorhabditis elegans DAF-16/FOXO transcription factor and its mammalian homologs associate with age-related disease (Q26781364)

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Mitochondrial reactive oxygen species are required for hypoxic HIF alpha stabilization.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

DAF-16 target identification in C. elegans: past, present and future

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

SMK-1, an essential regulator of DAF-16-mediated longevity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Unravelling the tumor-suppressive functions of FOXO proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Small heat-shock proteins and their potential role in human disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

mTOR is a key modulator of ageing and age-related disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXO-binding partners: it takes two to tango

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

PUMA, a potent killer with or without p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXO3A genotype is strongly associated with human longevity

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Association of FOXO3A variation with human longevity confirmed in German centenarians

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Reduced IGF signaling prevents muscle cell death in a Caenorhabditis elegans model of muscular dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Chaperone function and mechanism of small heat-shock proteins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Mutations that increase the life span of C. elegans inhibit tumor growth.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXOs attenuate bone formation by suppressing Wnt signaling.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Molecular origin of polyglutamine aggregation in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Daf-2 signaling modifies mutant SOD1 toxicity in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021

Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.EXGER.2015.09.006

7 January 2021