The role of activation-induced deaminase in antibody diversification and chromosome translocations (Q36845661)

16 August 2017

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title

The role of activation-induced deaminase in antibody diversification and chromosome translocations (English)

1 reference

Bernardo Reina San-Martin

16 August 2017

1 reference

object named as

Bernardo Reina San-Martin

2

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Michel C. Nussenzweig

7

object named as

Michel C Nussenzweig

1 reference

16 August 2017

Almudena Ramiro

1

1 reference

16 August 2017

Kevin McBride

3

1 reference

16 August 2017

Mila Jankovic

4

1 reference

16 August 2017

Vasco Barreto

5

1 reference

16 August 2017

André Nussenzweig

6

1 reference

16 August 2017

1 January 2007

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16 August 2017

Advances in Immunology

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16 August 2017

94

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16 August 2017

75-107

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Increased transcription levels induce higher mutation rates in a hypermutating cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID from bony fish catalyzes class switch recombination

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced deaminase: controversies and open questions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The mechanisms of immune diversification and their disorders

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced deaminase: light and dark sides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

1 reference

7 January 2021

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

H2AX: the histone guardian of the genome

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The balance between Pax5 and Id2 activities is the key to AID gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID to overcome the limitations of genomic information

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Structural phylogenetic analysis of activation-induced deaminase function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Shutdown of class switch recombination by deletion of a switch region control element.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation in normal and transformed human B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Nibrin functions in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Mechanisms of B-cell lymphoma pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Mechanisms of chromosomal translocations in B cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Delineation of the role of the Mre11 complex in class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The generation of antibody diversity through somatic hypermutation and class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation of the AID transgene in B and non-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Antibody regulation of B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

53BP1, an activator of ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Negative regulation of activation-induced cytidine deaminase in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Histone modifications associated with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The AID enzyme induces class switch recombination in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Constitutive expression of AID leads to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID mutates a non-immunoglobulin transgene independent of chromosomal position.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Recombinogenic phenotype of human activation-induced cytosine deaminase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Neoplastic development in plasma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID is required for c-myc/IgH chromosome translocations in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Genomic instability due to V(D)J recombination-associated transposition.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

ATM is required for efficient recombination between immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Chromosomal translocations deregulating c-myc are associated with normal immune responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Tissue-specific sensitivity to AID expression in transgenic mouse models.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Genome-wide somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Identification of a specific domain required for dimerization of activation-induced cytidine deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID-dependent histone acetylation is detected in immunoglobulin S regions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Predominant autoantibody production by early human B cell precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Domain organization of activation-induced cytidine deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994003-6

7 January 2021

10.1016/S0065-2776(06)94003-6

Identifiers

DOI

1 reference

16 August 2017

1 reference