The AID dilemma: infection, or cancer? (Q37994927)

26 August 2017

title

The AID dilemma: infection, or cancer? (English)

1 reference

26 August 2017

1

Tasuku Honjo

1 reference

26 August 2017

Maki Kobayashi

2

1 reference

26 August 2017

Nasim Begum

3

1 reference

26 August 2017

Ai Kotani

4

1 reference

26 August 2017

Somayeh Sabouri

5

1 reference

26 August 2017

Hitoshi Nagaoka

6

1 reference

26 August 2017

publication date

1 January 2012

1 reference

Advances in Cancer Research

26 August 2017

published in

1 reference

26 August 2017

volume

113

1 reference

26 August 2017

page(s)

1-44

1 reference

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

26 August 2017

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/35000501

Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis

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12 October 2022

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Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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12 October 2022

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A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Deletions in the constant region locus can account for switches in immunoglobulin heavy chain expression

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Discrete DNA sites regulate global distribution of meiotic recombination

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The Sμ Tandem Repeat Region Is Critical for Ig Isotype Switching in the Absence of Msh2

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

V(D)J recombination: RAG proteins, repair factors, and regulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Biology of Hodgkin's lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation induced cytidine deaminase expression in lymphocyte predominant Hodgkin lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Expression of activation-induced cytidine deaminase (AID) in Burkitt lymphoma cells: rare AID-negative cell lines with the unmutated rearranged VH gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Estrogen directly activates AID transcription and function

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Carboxy-terminal domain of AID required for its mRNA complex formation in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Expression of the AID protein in normal and neoplastic B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Prdm9 controls activation of mammalian recombination hotspots

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Cutting edge: CTNNBL1 is dispensable for Ig class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mantle cell lymphoma with t(11;14) and unmutated or mutated VH genes expresses AID and undergoes isotype switch events

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase: structure-function relationship as based on the study of mutants

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

CtIP promotes microhomology-mediated alternative end joining during class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hepatitis C and B-cell lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Immunity through DNA deamination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Constitutive expression of AID leads to tumorigenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Human Ape2 protein has a 3'-5' exonuclease activity that acts preferentially on mismatched base pairs

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hodgkin and Reed-Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Discovery of activation-induced cytidine deaminase, the engraver of antibody memory

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

High levels of activation-induced cytidine deaminase expression in adult T-cell leukaemia/lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Testing gene function early in the B cell lineage in mb1-cre mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

RAG1 core and V(D)J recombination signal sequences were derived from Transib transposons

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Organization of immunoglobulin heavy chain genes and allelic deletion model

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The connection between transcription and genomic instability

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Regulation of class switch recombination and somatic mutation by AID phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Regulation of AID expression in the immune response

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The mechanism and regulation of chromosomal V(D)J recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID to overcome the limitations of genomic information

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Two levels of protection for the B cell genome during somatic hypermutation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mechanisms of chromosomal translocations in B cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Shutdown of class switch recombination by deletion of a switch region control element.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The double-edged sword of activation-induced cytidine deaminase.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID is required for c-myc/IgH chromosome translocations in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Recombinogenic phenotype of human activation-induced cytosine deaminase.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Differential expression of activation-induced cytidine deaminase (AID) in nodular lymphocyte-predominant and classical Hodgkin lymphoma.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

A novel human B cell subpopulation representing the initial germinal center population to express AID.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

DNA sequences at immunoglobulin switch region recombination sites

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

WHO-EORTC classification for cutaneous lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Clonal selection and learning in the antibody system

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The AID enzyme induces class switch recombination in fibroblasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Chronic lymphocytic leukaemia: one disease or two?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Exon shuffling generates an immunoglobulin heavy chain gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Immunoglobulin class-switch recombination occurs in mantle cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The role of gene deletion in the immunoglobulin heavy chain switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Primary cutaneous follicle center lymphoma and primary cutaneous large B-cell lymphoma, leg type, are both targeted by aberrant somatic hypermutation but demonstrate differential expression of AID.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Uracil DNA N-glycosylase promotes assembly of human centromere protein A

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Role for topoisomerase 1 in transcription-associated mutagenesis in yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

The involvement of non-B DNA structures in gross chromosomal rearrangements

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Activation-induced cytidine deaminase expression in gastric cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Antigen receptor genes and the evolution of a recombinase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/B978-0-12-394280-7.00001-4

Identifiers

DOI

10.1016/B978-0-12-394280-7.00001-4

1 reference

26 August 2017

1 reference