Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease (Q38681728)

5 September 2017

Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease (English)

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5 September 2017

Xuetao Cao

1

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5 September 2017

1 December 2015

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Nature Reviews Immunology

5 September 2017

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5 September 2017

16

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5 September 2017

1

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5 September 2017

35-50

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https://scigraph.springernature.com/pub.10.1038/nri.2015.8

5 September 2017

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Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

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Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

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Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages

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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

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Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

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Epigenetic control of myeloid cell differentiation, identity and function.

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Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

21 January 2018

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Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.

21 January 2018

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Phenotypic plasticity and the epigenetics of human disease

21 January 2018

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New nomenclature for chromatin-modifying enzymes

21 January 2018

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The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis.

21 January 2018

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MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.

21 January 2018

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The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

21 January 2018

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The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

21 January 2018

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Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

21 January 2018

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The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.

21 January 2018

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Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip

21 January 2018

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Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2015.8

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

21 January 2018

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HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

21 January 2018

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

21 January 2018

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BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

21 January 2018

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Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation

21 January 2018

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Noncoding RNA and its associated proteins as regulatory elements of the immune system.

21 January 2018

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A long noncoding RNA mediates both activation and repression of immune response genes

21 January 2018

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A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

21 January 2018

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The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL.

21 January 2018

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Unconventional post-translational modifications in immunological signaling

21 January 2018

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

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Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

21 January 2018

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The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

21 January 2018

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

21 January 2018

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Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

21 January 2018

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The E3 ubiquitin ligase AMFR and INSIG1 bridge the activation of TBK1 kinase by modifying the adaptor STING.

21 January 2018

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21 January 2018

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Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Regulation of NF-kappaB activity through lysine monomethylation of p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Immune regulation of metabolic homeostasis in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Dendritic cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-κB activation and enhancing autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Targeted prostaglandin E2 inhibition enhances antiviral immunity through induction of type I interferon and apoptosis in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2015.8

Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Signaling by ROS drives inflammasome activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2015.8

Ubiquitin signalling in the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

DUBA: a deubiquitinase that regulates type I interferon production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Zinc finger protein ZBTB20 promotes Toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Activation and regulation of the inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Endotoxin tolerance: new mechanisms, molecules and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Negative regulation of TLR9-mediated IFN-alpha induction by a small-molecule, synthetic TLR7 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

IFNs activate toll-like receptor gene expression in viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Influenza a viruses upregulate neutrophil toll-like receptor 2 expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Role of tissue protection in lethal respiratory viral-bacterial coinfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Complement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Microbial manipulation of receptor crosstalk in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor 4 induced FcgammaR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcgammaR expression by interleukin 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Immune complex/Ig negatively regulate TLR4-triggered inflammatory response in macrophages through Fc gamma RIIb-dependent PGE2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Genetic variation in Toll-like receptors and disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Barrier-protective function of intestinal epithelial Toll-like receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor signaling inhibits hepatitis B virus replication in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2015.8

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2015.8

Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Polymorphisms of toll-like receptors and their pathways in viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Inflammasome biology in fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Mechanisms of disease: Toll-like receptors in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The immune system in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

c-FLIP-Short reduces type I interferon production and increases viremia with coxsackievirus B3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Characterization of retinoic acid-inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor 4 is involved in neuroprotection afforded by ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Pathogenesis of acute stroke and the role of inflammasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Targeting Toll-like receptors for treatment of SLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Emerging role of Toll-like receptors in the control of pain and itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Innate sensors of pathogen and stress: linking inflammation to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Innate immunity and adipocyte function: ligand-specific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptor 3 gene polymorphisms in South African Blacks with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptors and type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Acetylation of MKP-1 and the control of inflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Expression of MHC class II molecules contributes to lipopolysaccharide responsiveness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

RIG-I has guts: identification of a role for RIG-I in colitis development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Toll-like receptors and myocardial inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Initial immunopathogenesis of multiple sclerosis: innate immune response.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Cutting Edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2015.8

Microbial hijacking of complement-toll-like receptor crosstalk

31 March 2020

1 reference

12 December 2020

LPS induces CD14 association with complement receptor type 3, which is reversed by neutrophil adhesion

1 reference

12 December 2020

Toll-like receptors in liver fibrosis: cellular crosstalk and mechanisms

1 reference

12 December 2020

Associations between TLR polymorphisms and systemic lupus erythematosus: a systematic review and meta-analysis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI.2015.8

1 reference

PubMed ID

26711677

Dimensions Publication ID

5 September 2017

0 references

1 reference

PubMed ID

26711677